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<i>Artemisia austroyunnanensis<_i> Y. Ling

" in MedChemExpress (MCE) Product Catalog:

By Targets:	11β-HSD (1) 5 alpha Reductase (8) 5-HT Receptor (10) Acetyl-CoA Carboxylase (1) Ack1 (1) Acyltransferase (1) ADAMTS (2) ADC Antibody (1) ADC Cytotoxin (39) ADC Linker (4) Adenosine Deaminase (1) Adenosine Receptor (5) Adenylate Cyclase (3) Adrenergic Receptor (17) AIM2 (2) Akt (12) Aldose Reductase (1) Amino Acid Derivatives (188) Aminopeptidase (1) AMPK (11) Amylases (1) Amyloid-β (20) Anaplastic lymphoma kinase (ALK) (3) Androgen Receptor (4) Angiotensin Receptor (19) Angiotensin-converting Enzyme (ACE) (32) Antibiotic (56) Antibody-Drug Conjugates (ADCs) (5) Apoptosis (223) Arenavirus (4) Arginase (5) Arrestin (2) Aryl Hydrocarbon Receptor (4) Atg8/LC3 (5) ATM/ATR (5) Aurora Kinase (7) Autophagy (90) Bacterial (101) Bcl-2 Family (13) BCL6 (2) Bcr-Abl (27) Beta-lactamase (1) Beta-secretase (3) Biochemical Assay Reagents (48) Bradykinin Receptor (2) Btk (8) c-Fms (1) c-Kit (3) c-Met/HGFR (3) c-Myc (2) Calcium Channel (24) CaMK (4) Carbonic Anhydrase (65) Carboxylesterase (2) Carboxypeptidase (1) Casein Kinase (6) Caspase (12) CaSR (1) Cathepsin (2) CCR (3) CD19 (5) CD20 (1) CDK (22) Ceramidase (1) CFTR (2) Checkpoint Kinase (Chk) (1) Chloride Channel (1) Cholecystokinin Receptor (6) Cholinesterase (ChE) (26) CMV (1) Complement System (2) Constitutive Androstane Receptor (1) COX (15) CRFR (8) Cuproptosis (2) CXCR (14) Cyclic GMP-AMP Synthase (1) Cyclin G-associated Kinase (GAK) (1) Cytochrome P450 (13) Dengue virus (4) Deubiquitinase (5) DGK (2) Dihydrofolate reductase (DHFR) (2) Dipeptidyl Peptidase (2) Discoidin Domain Receptor (2) DNA Methyltransferase (1) DNA Stain (1) DNA-PK (4) DNA/RNA Synthesis (57) Dopamine Receptor (3) Dopamine Transporter (2) Drug Metabolite (7) Drug-Linker Conjugates for ADC (31) Dynamin (11) E1/E2/E3 Enzyme (4) E3 Ligase Ligand-Linker Conjugates (2) EAAT (1) EBV (1) EGFR (16) Elastase (3) Endogenous Metabolite (165) Endothelin Receptor (7) Enterovirus (2) Epigenetic Reader Domain (42) ERK (11) Estrogen Receptor/ERR (6) Eukaryotic Initiation Factor (eIF) (1) FAAH (1) Factor Xa (3) FAK (9) FAP (3) Farnesyl Transferase (6) Fatty Acid Synthase (FASN) (4) Ferroptosis (20) FGFR (6) Filovirus (4) Flavivirus (4) FLT3 (34) Fluorescent Dye (160) Formyl Peptide Receptor (FPR) (2) Free Fatty Acid Receptor (1) Fungal (43) FXR (2) G Protein-coupled Receptor Kinase (GRK) (2) G-quadruplex (1) GABA Receptor (4) GCGR (2) GHSR (3) GLP Receptor (7) Glucokinase (1) Glucosidase (13) Glucosylceramide Synthase (GCS) (4) GLUT (4) Glutaminase (2) Glutathione Peroxidase (5) Glutathione S-transferase (1) Glyoxalase (GLO) (11) GlyT (4) GnRH Receptor (3) GPR119 (1) GSK-3 (8) Guanylate Cyclase (3) HBV (12) HCV (14) HDAC (50) HIF/HIF Prolyl-Hydroxylase (6) Hippo (MST) (1) Histamine Receptor (3) Histone Acetyltransferase (2) Histone Demethylase (2) Histone Methyltransferase (25) HIV (52) HIV Integrase (6) HIV Protease (2) HMG-CoA Reductase (HMGCR) (1) HPV (3) HSP (7) HSV (1) IFNAR (7) IGF-1R (7) iGluR (9) IKK (24) Imidazoline 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Species (30) Renin (4) RET (1) Reverse Transcriptase (5) RIP kinase (5) ROCK (13) ROR (1) ROS Kinase (4) RSV (2) SARS-CoV (9) Ser/Thr Protease (1) Serotonin Transporter (2) SF3B1 (1) SHMT (1) SHP2 (2) Sirtuin (2) Small Interfering RNA (siRNA) (24) Sodium Channel (20) Somatostatin Receptor (2) SphK (4) Src (4) STAT (19) Stearoyl-CoA Desaturase (SCD) (1) Steroid Sulfatase (1) STING (13) Survivin (2) TAM Receptor (3) TGF-beta/Smad (6) TGF-β Receptor (31) TMV (3) TNF Receptor (21) Toll-like Receptor (TLR) (13) Topoisomerase (175) Transthyretin (TTR) (5) Trk Receptor (5) TROP2 (1) TRP Channel (6) TrxR (2) Tyrosinase (3) URAT1 (1) VD/VDR (3) VEGFR (10) Wnt (4) Xanthine Oxidase (3) YAP (3) α-synuclein (2) β-catenin (2) γ-secretase (4)
By Research Areas:	Cancer (1181) Cardiovascular Disease (246) Endocrinology (90) Infection (291) Inflammation/Immunology (401) Metabolic Disease (225) Neurological Disease (378)
Click Chemistry:	TCO (1) DBCO (1) Azide (21) Tetrazine (1) Alkynes (17)
Oligonucleotides:	miRNA mimics (10) Nucleosides and their Analogs (32) miRNA antagomirs (10) Nucleoside Phosphoramidites (5) Flavoring Agents (1) miRNA inhibitors (10) Phospholipids (2) mRNA (3) Antisense Oligonucleotides (2) siRNAs (23) Nucleotides and their Analogs (2) miRNA agomirs (10) MicroRNAs (40) Aptamers (5) Pre-designed siRNA Sets (23)

2965

Inhibitors & Agonists

Screening Libraries

148

Fluorescent Dye

Biochemical Assay Reagents

485

Peptides

MCE Kits

Inhibitory Antibodies

487

Natural
Products

386

Recombinant Proteins

126

Isotope-Labeled Compounds

150

Antibodies

Click Chemistry

115

Oligonucleotides

Cdk5i peptide	CDK	Neurological Disease
Cdk5i peptide is a 12-amino acid peptide fragment derived from Cdk5. Cdk5i peptide is an inhibitor of Cdk5 peptide. Cdk5i peptide can be used in the stud y of neurodegenerative diseases .

hCA I-IN-1	Carbonic Anhydrase	Cancer
hCA I-IN-1 (Compound 6q) is a human carbonic anhydrase I (hCA I) inhibitor with K_i values of 38.3, 716.4, 940.1 and 192.8 nM against hCA I, hCA II, hCAIX and hCAXII, respectively .

hCA I-IN-2	Carbonic Anhydrase	Cancer
hCA I-IN-2 (Compound 6d) is a selective human carbonic anhydrase I (hCA I) inhibitor with K_i values of 18.8, 375.1, 1721 and 283.9 nM against hCA I, hCA II, hCAIX and hCAXII, respectively .

Topoisomerase I inhibitor 11	Topoisomerase Btk	Cancer
Topoisomerase I inhibitor 11 is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 11 can bind to BTK .

Topoisomerase I inhibitor 13	Topoisomerase	Cancer
Topoisomerase I inhibitor 13 (Compound G11) is a Topo I inhibitor that inhibits cancer cell proliferation. Topoisomerase I inhibitor 13 significantly inhibits tumor growth in vivo .

Momordicine I	DGK	Metabolic Disease
Momordicine I, a triterpenoid compound extracted from momordica charantia L. Momordicine I alleviates isoproterenol-induced cardiomyocyte hypertrophy through suppression of PLA2G6 and DGK-ζ .

Tenaxin I	Others	Others
Tenaxin I is a component extracted from Radix Scutellariae with neuraminidase inhibitory activity .

Topoisomerase I inhibitor 6	Topoisomerase	Cancer
Topoisomerase I inhibitor 6 (Compound 3) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 6 is able to trap DNA-Top1 cleavage complex and found to be less cytotoxic in non-cancerous cell line. Topoisomerase I inhibitor 6 has the potential for the research of cancer diseases .

Biotinyl-Angiotensin I (human, mouse, rat)	Endogenous Metabolite	Endocrinology
Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .

Topoisomerase I/II inhibitor 4	Topoisomerase Apoptosis	Cancer
Topoisomerase I/II inhibitor 4 (compound F16) is a potent topoisomerase I (Topo I) and II (Topo II) dual inhibitor. Topoisomerase I/II inhibitor 4 inhibits cell proliferation, invasion and migration and induces apoptosis. Topoisomerase I/II inhibitor 4 can be used for liver cancer research .

Topoisomerase I inhibitor 7	Topoisomerase	Cancer
Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor agent candidates among the heteroarene-fused anthraquinones .

Topo I/COX-2-IN-1	Topoisomerase Prostaglandin Receptor Apoptosis	Inflammation/Immunology Cancer
Topo I/COX-2-IN-1 (1H-30) is a potential Topo I/COX-2 inhibitor. Topo I/COX-2-IN-1 inhibits COX-2 and Topo I with the IC₅₀ value of 0.24 μM and 4.42 μM, respectively. Topo I/COX-2-IN-1 can induce apoptosis and inhibit migration of cancer cells, has anti-cancer activity .

I-152	Keap1-Nrf2	Metabolic Disease
I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). I-152 activates NRF2 and ATF4 signals. I-152 has anti-proliferative properties .

Endoglycoceramidase I (EGCase I)	Endogenous Metabolite	Metabolic Disease
Endoglycoceramidase I (EGCase I) is a glycosidase, is often used in biochemical studies. Endoglycoceramidase I catalyzes a transglycosylation reaction, which transfers the sugar moiety of GSLs to the primary hydroxyl group of several 1-alkanols .

Topoisomerase I inhibitor 2	Topoisomerase Apoptosis Caspase	Cancer
Topoisomerase I inhibitor 2 (ZML-8) is a highly selective inhibitor of DNA topoisomerase I (Top1). Topoisomerase I inhibitor 2 inhibits Top1 activity and results DNA damage. Topoisomerase I inhibitor 2 blocks G2/M phase and induces apoptosis, exhibits anti-tumor effect .

Fasciculin-I FAS-I	Cholinesterase (ChE)	Neurological Disease
Fasciculin-I is isolated from the mambas venom. Fasciculin-I exerts its toxic effects by inhibiting acetylcholinesterase (AChE). Fasciculin-I blocks α-neurotoxins of nicotinic acetylcholine receptors and cardiac toxins that interact with cell membranes .

Glyoxalase I Glo-I	Others	Others
Glyoxalase I (Glo-I) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Huwentoxin I HWTX-I	Calcium Channel Sodium Channel	Neurological Disease
Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC₅₀ values of 66.1 and 4.80 nM, respectively .

Maackia Amurensis Lectin I MAL I	Fluorescent Dye	Others
Maackia Amurensis Lectin I (MAL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin I (MAL I) is a biological material or organic compound that can be used in life science research .

Ricinus Communis Agglutinin I RCA I	Fluorescent Dye	Others
Ricinus Communis Agglutinin I (RCA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) is a biological material or organic compound that can be used in life science research .

Ulex Europaeus Agglutinin I UEA I	Fluorescent Dye	Others
Ulex Europaeus Agglutinin I (UEA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) is a biological material or organic compound that can be used in life science research .

Monofucosyllacto-N-hexaose I MFLNH I	Others	Others
Monofucosyllacto-N-hexaose I (MFLNH I) is a composition of human milk oligosaccharide .

Aristolactam I (Standard)	Caspase Apoptosis	Inflammation/Immunology
Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway .

LQZ-7I	Survivin	Cancer
LQZ-7I is a survivin-targeting inhibitor. LQZ-7I inhibits survivin dimerization. LQZ-7I orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors .

Dendrotoxin-I DTX-I	Potassium Channel	Neurological Disease Cancer
Dendrotoxin-I (DTX-I) is a potent K ⁺ channels blocker with IC₅₀s of 0.13-50 nM for voltage-gated potassium channel subunits K_V1.1, K_V1.2 and K_V1.6, respectively. Dendrotoxin-I, a neurotoxin, has the potential for cancer research .

Schibitubin I	Others	Neurological Disease
Schibitubin I is a lignin. Schibitubin I has neuroprotective activity. Schibitubin I can be isolated from the fruits of Schisandra bicolor var. tuberculata .

Recombinant endoglycoceramidase I rEGCase I	Biochemical Assay Reagents	Metabolic Disease
Recombinant endoglycoceramidase I (rEGCase I) is a glycosidase that catalyzes the hydrolysis of the β-glycosidic linkage between oligosaccharides and ceramides. Recombinant endoglycoceramidase I catalyzes a transglycosylation reaction, which transfers the sugar moiety of glycosphingolipids (GSLs) to the primary hydroxyl group of several 1-alkanols .

Griffonia (Bandeiraea) Simplicifolia Lectin I GSL I	Fluorescent Dye	Others
Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a biological material or organic compound that can be used in life science research .

Okaramine I	Bacterial	Infection
Okaramine I is an Escherichia coli glycosyltransferase (MurG) inhibitor. Okaramine I can be used as an antibacterial agent. Okaramine I can be found in Aspergillus aculeatus .

Goshuyuamide I	Others	Others
Goshuyuamide-I (compound 4) is a kind of alkaloid. Goshuyuamide-I can be isolated from the fruits of Euodia rutaecarpa. Goshuyuamide-I can be used in the research of analgesics .

BH3I-2'	Others	Cancer
BH3I-2' is the BH3I-2 analogue. BH3I-2 is a Bcl-2 family inhibitor. BH3I-2' can be used for various studies .

Dehydrosoyasaponin I Soyasaponin Be; DHS-I	Potassium Channel	Neurological Disease
Dehydrosoyasaponin I (Soyasaponin Be;DHS-I), a triterpene glycoside, is a potent and reversible calcium-activated potassium (maxi-K) channels activator .

Urechistachykinin I Uru-TK I	Bacterial	Infection
Urechistachykinin I (Uru-TK I), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .

Picroside I (Standard)	STAT	Inflammation/Immunology
Picroside I (Standard) is the analytical standard of Picroside I. This product is intended for research and analytical applications. Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II . Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ .

Maackia Amurensis Lectin I (Fluorescein) MAL I (Fluorescein)	Fluorescent Dye	Others
Maackia Amurensis Lectin I (MAL I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin I (MAL I) Fluorescein is a biological material or organic compound that can be used in life science research .

Ricinus Communis Agglutinin I (Fluorescein) RCA I (Fluorescein)	Fluorescent Dye	Others
Ricinus Communis Agglutinin I (RCA I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Fluorescein is a biological material or organic compound that can be used in life science research .

Ulex Europaeus Agglutinin I (Fluorescein) UEA I (Fluorescein)	Fluorescent Dye	Others
Ulex Europaeus Agglutinin I (UEA I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Fluorescein is a biological material or organic compound that can be used in life science research .

Ricinus Communis Agglutinin I (Rhodamine) RCA I (Rhodamine)	Fluorescent Dye	Others
Ricinus Communis Agglutinin I (RCA I) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Rhodamine is a biological material or organic compound that can be used in life science research .

Ulex Europaeus Agglutinin I (Rhodamine) UEA I (Rhodamine)	Fluorescent Dye	Others
Ulex Europaeus Agglutinin I (UEA I) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Rhodamine is a biological material or organic compound that can be used in life science research .

Ulex Europaeus Agglutinin I (Agarose) UEA I (Agarose)	Fluorescent Dye	Others
Ulex Europaeus Agglutinin I (UEA I) Agarose is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Agarose is a biological material or organic compound that can be used in life science research .

Ricinus Communis Agglutinin I (Agarose) RCA I (Agarose)	Fluorescent Dye	Others
Ricinus Communis Agglutinin I (RCA I) Agarose is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Agarose is a biological material or organic compound that can be used in life science research .

Ricinus Communis Agglutinin I (Biotinylated) RCA I (Biotinylated)	Fluorescent Dye	Others
Ricinus Communis Agglutinin I (RCA I) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Biotinylated is a biological material or organic compound that can be used in life science research .

Ulex Europaeus Agglutinin I (Biotinylated) UEA I (Biotinylated)	Fluorescent Dye	Others
Ulex Europaeus Agglutinin I (UEA I) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Biotinylated is a biological material or organic compound that can be used in life science research .

Aristolactam I 1 Publications Verification Aristololactam; Aristolactam	Caspase Apoptosis	Inflammation/Immunology
Aristololactam I (AL-I), is the main metabolite of aristolochic acid I (AA-I), participates in the processes that lead to renal damage. Aristololactam I (AL-I) directly injures renal proximal tubule cells, the cytotoxic potency of AL-I is higher than that of AA-I and that the cytotoxic effects of these molecules are mediated through the induction of apoptosis in a caspase-3-dependent pathway .

LU-002i	Proteasome	Others
LU-002i is a subunit-selective human proteasome β2c and β2i inhibitor with an IC₅₀ value of 220 nM for β2i .

Pyronin Y 3 Publications Verification Pyronine G; C.I. 45005	DNA Stain	Others
Pyronin Y (Pyronine G) is a cationic dye that intercalates RNA and has been used to target cell structures including RNA, DNA and organelles. Pyronin Y forms fluorescent complexes with double-stranded nucleic acids (especially RNA) enabling semi-quantitative analysis of cellular RNA. Pyronin Y can be used to identify specific RNA subspecies of ribonuclear proteins complexes in live cells .

Cat. No.	Product Name

HY-L035P

Drug Repurposing Compound Library Plus

5,815 compounds

New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved and clinical drugs, especially after phase I drugs, have identified bioactivities, good pharmacokinetic characteristics and safety, which are suitable for drug repurposing.

MCE Drug Repurposing Compound Library plus contains 5,815 approved and passed phase I clinical drugs, which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties.

MCE Drug Repurposing Compound Library plus, with more powerful screening capability, further complement MCE Drug Repurposing Compound Library (HY-L035) by adding some compounds with low solubility or stability (Part B) to this library. All those supplementary compounds are supplied in powder form.

HY-L035

Drug Repurposing Compound Library

4,971 compounds

MCE Drug Repurposing Compound Library contains 4,971 approved drugs and passed phase Ⅰclinical drugs, which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties.

HY-L018

TGF-beta/Smad Compound Library

243 compounds

The transforming growth factor beta (TGF-β) signaling pathway is involved in many cellular processes in both the adult organism and the developing embryo including cell growth, cell differentiation, apoptosis, cellular homeostasis and other cellular functions. The TGF-β superfamily comprises TGF-βs, bone morphogenetic proteins (BMPs), activins and related proteins. Signaling begins with the binding of a TGF beta superfamily ligand to a TGF beta type II receptor. The type II receptor is a serine/threonine receptor kinase, which catalyzes the phosphorylation of the Type I receptor. The type I receptor then phosphorylates receptor-regulated SMADs (R-SMADs) which can now bind the coSMAD (e.g. SMAD4). R-SMAD/coSMAD complexes accumulate in the nucleus where they act as transcription factors and participate in the regulation of target gene expression. Deregulation of TGF-β signaling contributes to developmental defects and human diseases, including cancers, some bone diseases, chronic kidney disease, etc.

MCE designs a unique collection of 243 TGF-beta/Smad signaling pathway compounds. TGF-beta/Smad Compound Library acts as a useful tool for TGF-beta/Smad-related drug screening and disease research.

HY-L040

Anti-diabetic Compound Library

771 compounds

Diabetes mellitus, usually called diabetes, is a group of metabolic disorders characterized by a high blood sugar level over a prolonged period of time. The most common types are Type I and Type II. Type I diabetes (T1D), also called juvenile onset diabetes mellitus or insulin-dependent diabetes mellitus, is characterized by destruction of the β-cells of the pancreas and insulin is not produced, whereas type II diabetes (T2D), also called non-insulin-dependent diabetes mellitus, is characterized by a progressive impairment of insulin secretion and relative decreased sensitivity of target tissues to the action of this hormone. Type 2 diabetes accounts for the vast majority of all diabetes mellitus. Diabetes of all types can lead to complications in many parts of the body and can increase the overall risk of dying prematurely. Possible complications include kidney failure, leg amputation, vision loss and nerve damage.

The pathogenesis of diabetes is complicated, and development of the safe and effective drugs against diabetes is full of challenge. Increasing studies have confirmed that the pathogenesis of diabetes is related to various signaling pathways, such as insulin signaling pathway, AMPK pathway, PPAR regulation and chromatin modification pathways. These signaling pathways have thus become the major source of the promising novel drug targets to treat metabolic diseases and diabetes.

MCE Anti-diabetic Compound Library owns a unique collection of 771 compounds, which mainly target SGLT, PPAR, DPP-4, AMPK, Dipeptidyl Peptidase, Glucagon Receptor, etc. This library is a useful tool for discovery anti-diabetes drugs.

HY-L118

Sodium Channel Blocker Library

139 compounds

Sodium channels conduct sodium ions (Na+) through a cell's plasma membrane that are the source of excitatory currents for the nervous system and muscle. Na channels are classified according to the trigger that opens the channel for such ions, i.e. either a voltage-change (Voltage-gated, voltage-sensitive, or voltage-dependent sodium channel also called VGSCs or Nav channel) or a binding of a substance (a ligand) to the channel (ligand-gated sodium channels). Dysfunction in voltage-gated sodium channels correlates with neurological and cardiac diseases, including epilepsy, myopathies, pain and cardiac arrhythmias. Sodium channel blockers are used in the treatment of cardiac arrhythmia, pain and convulsion.

MCE offers a unique collection of 139 sodium channel blocker and antagonists, all of which have the identified inhibitory effect on sodium channels. MCE Sodium Channel Blocker Library can be used for neurological and cardiac diseases drug discovery and sodium channel research.

HY-L022M

FDA-Approved Drug Library Mini

3,033 compounds

New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication. First, the risk of failure is lower. Second, the time frame for drug development can be reduced. Third, less investment is needed. Approved drugs have identified bioactivities, good pharmacokinetic characteristics and safety which are suitable for drug repurposing.

MCE owns a unique collection of 3,033 approved compounds which have been completed extensive preclinical and clinical studies and have well-characterized bioactivities, safety and bioavailability properties. The package of this library is 96-well microplate with peelable foil seal, which makes the screening process easier and faster.

HY-L065

Traditional Chinese Medicine Active Compound Library

2,908 compounds

Chinese herbal therapy is an important part of Traditional Chinese Medicine (TCM). It has been used for centuries in China, where herbs are considered fundamental therapy for many acute and chronic conditions. Many studies indicated TCM exerted an overall regulatory effect via multi-component and multi-target network. Active components from Traditional Chinese Medicine possess many medicinal properties such as antioxidant, anti-cancer, and anti-bacterial effects, which makes it an important source of new drugs. Nearly 200 modern medicines have been developed either directly or indirectly from the plants used as medicines in China. For example, artemisinin, used in multidrug resistant malaria, was first isolated from the Chinese herb Artemisia annua L. Today, scientists continue to identify compounds in Chinese herbal remedies that may be useful in the development of new therapeutic agents applicable in Western medicine.

MCE designs a unique collection of 2,908 active compounds of Chinese Herbal Medicines. MCE Traditional Chinese Medicine Active Compound Library is a useful tool for discovery new drugs from TCM.

HY-L076

Drug-Induced Liver Injury (DILI) Compound Library

1,417 compounds

Drug-induced liver injury (DILI; also known as drug-induced hepatotoxicity) is caused by medications (prescription or OTC), herbal and dietary supplements (HDS), or other xenobiotics that result in abnormalities in liver tests or in hepatic dysfunction that cannot be explained by other causes. Drugs are an important cause of liver injury. Drug-induced hepatic injury is the most common reason cited for withdrawal of an approved drug.

DILI is thought to occur via several different mechanisms. Among these are direct impairment of the structural (e.g., mitochondrial dysfunction) and functional integrity of the liver; production of a metabolite that alters hepatocellular structure and function; production of a reactive drug metabolite that binds to hepatic proteins to produce new antigenic drug-protein adducts, which are targeted by hosts’ defenses (the hapten hypothesis); and initiation of a systemic hypersensitivity response (i.e., drug allergy) that damages the liver.

MCE Drug-induced Liver Injury (DILI) Compound Library contains a unique collection of 1,417 hepatotoxicity causing compounds and is a powerful tool to research DILI and other drug toxicities. This library can be used to understand the mechanisms of DILI, identify biomarkers for early DILI prediction, and allow timely recognition during drug development, thus finally achieving successful DILI prevention and assessment in the pre-marketing phase.

HY-L073

Anti-Hepatitis C Virus Compound Library

304 compounds

Hepatitis C virus (HCV) is a hepatotropic enveloped positive- strand RNA virus (family Flaviviridae) that infects the parenchymal cells of the liver. HCV infection is a significant public health burden. Globally, an estimated 71 million people have chronic hepatitis C virus infection. A significant number of those who are chronically infected will develop cirrhosis or liver cancer. To date, there is no vaccine against HCV, and combination pegylated alpha interferon (pIFN-) and ribavirin, the main standard-of-care treatment for HCV, is effective in only a subset of patients and is associated with a wide spectrum of toxic side effects and complications. More recently, new therapeutic approaches that target essential components of the HCV life cycle have been developed, including direct-acting antiviral (DAA) that specifically block a viral enzyme or functional protein and host-targeted agents (HTA) that block interactions between host proteins and viral components that are essential to the viral life cycle. However, the genetic diversity of HCV viruses and the stage of liver disease (i.e., cirrhosis) are revealing themselves as obstacles for effective, pan-genotypic treatments. There still exists a need for the discovery and development of new HCV inhibitors. In particular, since the future of HCV therapy will likely consist of a cocktail approach using multiple inhibitors that target different steps of infection, new antivirals targeting all steps of the viral infection cycle.

MCE offers a unique collection of 304 compounds with identified and potential anti-HCV activity. MCE Anti- Hepatitis C Virus Compound Library is a useful tool for discovery new anti-HCV drugs and other anti-infection research.

Cat. No.	Product Name	Type

HY-D0971

Pyronin Y 3 Publications Verification Pyronine G; C.I. 45005	Fluorescent Dyes/Probes
Pyronin Y (Pyronine G) is a cationic dye that intercalates RNA and has been used to target cell structures including RNA, DNA and organelles. Pyronin Y forms fluorescent complexes with double-stranded nucleic acids (especially RNA) enabling semi-quantitative analysis of cellular RNA. Pyronin Y can be used to identify specific RNA subspecies of ribonuclear proteins complexes in live cells .

HY-D1148

HKGreen-4I 1 Publications Verification	Fluorescent Dyes/Probes
HKGreen-4I is a highly sensitive green fluorescent probe for the specific detection of ONOO ^- in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .

HY-D0024

Sudan I Solvent Yellow 14	Dyes
Sudan I (Solvent Yellow 14) is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .

HY-D0024R

Sudan I (Standard)	Dyes
Sudan I (Standard) is the analytical standard of Sudan I. This product is intended for research and analytical applications. Sudan I (Solvent Yellow 14) is a diazo-conjugate red dye and can be used as an additive to products such as oils, solvents or polishes. Sudan I inhibits growth of bacterial strains Clostridium perfringens and L. rhamnosus .

HY-D0140

Chromoionophore I ETH 5294	Fluorescent Dyes/Probes
Chromoionophore I (ETH 5294) is a hydrophobic pH indicator. Chromoionophore I is used as a transmissive or fluorescent probe molecule in many types of hydrophobic sensor membranes. Chromoionophore I is oil-soluble .

HY-D0497R

C.I. Disperse orange 37 (Standard)	Dyes
C.I. Disperse orange 37 (Standard) is the analytical standard of C.I. Disperse orange 37. This product is intended for research and analytical applications. C.I. Disperse orange 37 is an orange-orange dye commonly used for fiber dyeing.

HY-D0597

C.I. Mordant red 94	Dyes
C.I. Mordant red 94 is an azo dye.

HY-D0496

C.I. Mordant green 17	Dyes
C.I. Mordant green 17 is an azo dye.

HY-D0475

C.I.Solvent yellow 176	Dyes
C.I.Solvent yellow 176 is a quinoline dye.

HY-D0439

C.I. Mordant yellow 12	Dyes
C.I. Mordant yellow 12 is an azo dye.

HY-D0409

C.I. Mordant yellow 8	Dyes
C.I. Mordant yellow 8 is an azo dye.

HY-D0319

C.I. Basic Blue 8	Dyes
C.I. Basic Blue 8 is a basic dye.

HY-D0314R

Solvent Red 1 (C.I.) (Standard)	Dyes
Solvent Red 1 (C.I.) (Standard) is the analytical standard of Solvent Red 1 (C.I.). This product is intended for research and analytical applications. Solvent Red 1 (C.I.) is a red dye. Its series of products, such as Solvent orange 60 (HY-D1177), has been used in dyeing applications of plastic materials.

HY-D0413

C.I. Acid red 37	Dyes
C.I. Acid red 37 is an acid red dye that can be adsorbed and removed by bentone clay.

HY-D0536

C.I. Acid black 132	Dyes
C.I. Acid black 132 is an acidic black dye that can be adsorbed and removed by bentone.

HY-D0509

C.I. Acid yellow 172	Dyes
C.I. Acid yellow 172 is an acidic yellow dye that can be adsorbed and removed by bentone.

HY-D0508

C.I. Acid red 138	Dyes
C.I. Acid red 138 is an acid red dye that can be adsorbed and removed by bentone clay.

HY-D0494

C.I. Acid yellow 151	Dyes
C.I. Acid yellow 151 is an acidic yellow dye that can be adsorbed and removed by bentone.

HY-D0490

C.I. Acid yellow 49	Dyes
C.I. Acid yellow 49 is an acidic yellow dye that can be adsorbed and removed by bentone.

HY-D0480

C.I. Acid black 60	Dyes
C.I. Acid black 60 is an acidic black dye that can be adsorbed and removed by bentone.

HY-D0477

C.I. Acid red 57	Dyes
C.I. Acid red 57 is an acid red dye that can be adsorbed and removed by bentone clay.

HY-D0458

C.I. Acid red 106	Dyes
C.I. Acid red 106 is an acid red dye that can be adsorbed and removed by bentone clay.

HY-D0448

C.I. Acid red 154	Dyes
C.I. Acid red 154 is an acid red dye that can be adsorbed and removed by bentone clay.

HY-D0447

C.I. Acid red 374	Dyes
C.I. Acid red 374 is an acid red dye that can be adsorbed and removed by bentone clay.

HY-D0438

C.I. Acid red 114	Dyes
C.I. Acid red 114 is an acid red dye that can be adsorbed and removed by bentone clay.

HY-D0434

C.I. Acid blue 40 sodium salt	Dyes
C.I. Acid blue 40 sodium salt is an acidic blue dye that can be adsorbed and removed by bentone.

HY-D0424

C.I. Acid blue 25	Dyes
C.I. Acid blue 25 is an acidic blue dye that can be adsorbed and removed by bentone.

HY-D0423

C.I. Acid green 27	Dyes
C.I. Acid green 27 is an acidic green dye that can be adsorbed and removed by bentone.

HY-D0422

C.I. Acid red 183	Dyes
C.I. Acid red 183 is an acid red dye that can be adsorbed and removed by bentone clay.

HY-D0420

C.I. Acid red 151	Dyes
C.I. Acid red 151 is an acid red dye that can be adsorbed and removed by bentone clay.

HY-D0418

C.I. Acid yellow 42	Dyes
C.I. Acid yellow 42 is an acidic yellow dye that can be adsorbed and removed by bentone.

HY-D0412

C.I. Acid yellow 48	Dyes
C.I. Acid yellow 48 is an acidic yellow dye that can be adsorbed and removed by bentone.

HY-D0410

C.I. Acid yellow 200	Dyes
C.I. Acid yellow 200 is an acidic yellow dye that can be adsorbed and removed by bentone.

HY-D0495

C.I. Acid brown 83	Dyes
C.I. Acid brown 83 is an acidic brown dye that can be adsorbed and removed by bentone clay.

HY-D0481

C.I. Acid orange 67	Dyes
C.I. Acid orange 67 is an acidic orange-yellow dye that can be adsorbed and removed by bentone.

HY-D0452

C.I. Acid brown 75	Dyes
C.I. Acid brown 75 is an acidic brown dye that can be adsorbed and removed by bentone clay.

HY-D0446

C.I. Acid orange 33	Dyes
C.I. Acid orange 33 is an acidic orange-yellow dye that can be adsorbed and removed by bentone.

HY-D0444

C.I. Acid brown 121	Dyes
C.I. Acid brown 121 is an acidic brown dye that can be adsorbed and removed by bentone clay.

HY-D0435

C.I. Acid brown 120	Dyes
C.I. Acid brown 120 is an acidic brown dye that can be adsorbed and removed by bentone clay.

HY-D0417

C.I. Acid orange 3	Dyes
C.I. Acid orange 3 is an acidic orange-yellow dye that can be adsorbed and removed by bentone.

HY-D0929

Orange I α-Naphthol Orange	Dyes
Orange I (α-Naphthol Orange) is an organic azo dye used as a food dye .

HY-D0443

C.I. Direct black 22	Dyes
C.I. Direct black 22 is a good dyeing agent for cotton fabrics.

HY-D0482

C.I. Direct blue 80	Dyes
C.I. Direct blue 80 is a good dyeing agent for cotton fabrics.

HY-D0465

C.I. Direct black 80	Dyes
C.I. Direct black 80 is a good dyeing agent for cotton fabrics.

HY-D0451

C.I. Direct orange 102	Dyes
C.I. Direct orange 102 is a good dyeing agent for cotton fabrics.

HY-D0440

C.I. Direct green 28	Dyes
C.I. Direct green 28 is a good dyeing agent for cotton fabrics.

HY-D0437

C.I. Direct blue 75	Dyes
C.I. Direct blue 75 is a good dyeing agent for cotton fabrics.

HY-D0436

C.I. Direct black 32	Dyes
C.I. Direct black 32 is a good dyeing agent for cotton fabrics.

HY-D0425

C.I. Direct red 84	Dyes
C.I. Direct red 84 is a good dyeing agent for cotton fabrics.

HY-D0419

C.I. Direct green 26	Dyes
C.I. Direct green 26 is a good dyeing agent for cotton fabrics.

Cat. No.	Product Name	Type

HY-NP079

Ricinus Communis Agglutinin I RCA I	Native Proteins
Ricinus Communis Agglutinin I (RCA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) is a biological material or organic compound that can be used in life science research .

HY-NP072

Maackia Amurensis Lectin I MAL I	Native Proteins
Maackia Amurensis Lectin I (MAL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin I (MAL I) is a biological material or organic compound that can be used in life science research .

HY-NP090

Ulex Europaeus Agglutinin I UEA I	Native Proteins
Ulex Europaeus Agglutinin I (UEA I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) is a biological material or organic compound that can be used in life science research .

HY-NP068

Griffonia (Bandeiraea) Simplicifolia Lectin I GSL I	Native Proteins
Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) is a biological material or organic compound that can be used in life science research .

HY-NP0137

Maackia Amurensis Lectin I (Fluorescein) MAL I (Fluorescein)	Native Proteins
Maackia Amurensis Lectin I (MAL I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Maackia Amurensis Lectin I (MAL I) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-NP0141

Ricinus Communis Agglutinin I (Fluorescein) RCA I (Fluorescein)	Native Proteins
Ricinus Communis Agglutinin I (RCA I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-NP0145

Ulex Europaeus Agglutinin I (Fluorescein) UEA I (Fluorescein)	Native Proteins
Ulex Europaeus Agglutinin I (UEA I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-NP0157

Ricinus Communis Agglutinin I (Rhodamine) RCA I (Rhodamine)	Native Proteins
Ricinus Communis Agglutinin I (RCA I) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Rhodamine is a biological material or organic compound that can be used in life science research .

HY-NP0158

Ulex Europaeus Agglutinin I (Rhodamine) UEA I (Rhodamine)	Native Proteins
Ulex Europaeus Agglutinin I (UEA I) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Rhodamine is a biological material or organic compound that can be used in life science research .

HY-NP0168

Ulex Europaeus Agglutinin I (Agarose) UEA I (Agarose)	Native Proteins
Ulex Europaeus Agglutinin I (UEA I) Agarose is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Agarose is a biological material or organic compound that can be used in life science research .

HY-NP0172

Ricinus Communis Agglutinin I (Agarose) RCA I (Agarose)	Native Proteins
Ricinus Communis Agglutinin I (RCA I) Agarose is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Agarose is a biological material or organic compound that can be used in life science research .

HY-NP0186

Ricinus Communis Agglutinin I (Biotinylated) RCA I (Biotinylated)	Native Proteins
Ricinus Communis Agglutinin I (RCA I) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ricinus Communis Agglutinin I (RCA I) Biotinylated is a biological material or organic compound that can be used in life science research .

HY-NP0190

Ulex Europaeus Agglutinin I (Biotinylated) UEA I (Biotinylated)	Native Proteins
Ulex Europaeus Agglutinin I (UEA I) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Ulex Europaeus Agglutinin I (UEA I) Biotinylated is a biological material or organic compound that can be used in life science research .

HY-NP0131

Griffonia (Bandeiraea) Simplicifolia Lectin I (Fluorescein) GSL I (Fluorescein)	Native Proteins
Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-NP0155

Griffonia (Bandeiraea) Simplicifolia Lectin I (Rhodamine) GSL I (Rhodamine)	Native Proteins
Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) Rhodamine is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia (Bandeiraea) Simplicifolia Lectin I (GSL I) Rhodamine is a biological material or organic compound that can be used in life science research .

HY-W013508

I2959	3D Bioprinting
I2959 is widely used as a photoinitiator for photochemical cross-linking of hydrogels, and the combination of I2959 and CMA hydrogel has been used as a bio-ink for biological 3D printing applications. In addition, I2959 has a high free radical generation efficiency and is cytotoxic to rapidly dividing cell lines .

HY-NP0178

Griffonia Simplicifolia Lectin I Isolectin B4 (Biotinylated) GSL I-B4 (Biotinylated)	Native Proteins
Griffonia Simplicifolia Lectin I Isolectin B4 (GSL I-B4) Biotinylated is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia Simplicifolia Lectin I Isolectin B4 (GSL I-B4) Biotinylated is a biological material or organic compound that can be used in life science research .

HY-NP101

Highly purified Type I collagen, from bovine skin Bovine Type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from bovine skin (Bovine Type I collagen, immunization grade) plays an important role in the structure and function of skin, bone, tendons, and many others. Type I collagen potently stimulates angiogenesis in vitro and in vivo. Highly purified Type I collagen, from bovine skin is an immunization grade that can be used for immunization to generate antibodies .

HY-NP0132

Griffonia Simplicifolia Lectin I Isolectin B4 (Fluorescein) GSL I Isolectin B4 (Fluorescein)	Native Proteins
Griffonia Simplicifolia Lectin I Isolectin B4 (GSL I Isolectin B4) Fluorescein is a plant lectin that can be used as a probe to specifically bind biomolecules (such as polysaccharides, peptides, etc.).Griffonia Simplicifolia Lectin I Isolectin B4 (GSL I Isolectin B4) Fluorescein is a biological material or organic compound that can be used in life science research .

HY-W073080

Coproporphyrin I dihydrochloride	Biochemical Assay Reagents
Coproporphyrin I dihydrochloride is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W127800

Etioporphyrin I	Biochemical Assay Reagents
Etioporphyrin I is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-NP085

Griffonia Simplicifolia Lectin I Isolectin B4 GSL I Isolectin B4	Native Proteins
Griffonia Simplicifolia Lectin I Isolectin B4 (GSL I Isolectin B4) is a lectin, that can be isolated from the seeds of Griffonia simplicifolia. Griffonia Simplicifolia Lectin I Isolectin B4 recognizes and binds to carbohydrate structures with the sequence Galα1-4Gal, and can be used in biochemical and immunological .

HY-P5282

ApoA-I mimetic peptide	Drug Delivery
ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyl transferase (LCAT) activation potency. ApoA-I mimetic peptide can be used for synthesis of peptide/lipid complex .

HY-W127805

Pentacarboxylporphyrin I dihydrochloride

Biochemical Assay Reagents

Pentacarboxylporphyrin I dihydrochloride is an organic compound belonging to the family of porphyrin derivatives. It is commonly used in biochemical research as a reference standard for the quantification of porphyrins and related compounds in biological samples. Pentacarboxylporphyrin I dihydrochloride has several applications in the diagnosis and monitoring of porphyrias, a group of inherited disorders characterized by abnormalities in heme metabolism. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.

HY-W344938R

C.I. Acid yellow 3 (Standard)	Indicators
C.I. Acid yellow 3 (Standard) is the analytical standard of C.I. Acid yellow 3. This product is intended for research and analytical applications. C.I. Acid yellow 3 is an anionic quinolinone dye that is commonly used as a food additive, but also in the cosmetic and pharmaceutical industries .

HY-W073069

Coproporphyrin I tetramethyl ester	Biochemical Assay Reagents
Coproporphyrin I tetramethyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W006103

I-bu-rG Phosphoramidite	Gene Sequencing and Synthesis
I-bu-rG Phosphoramidite is a phosphinamide monomer which can be used in the synthesis of nucleotides and nucleic acids.

HY-141627

Heparin disaccharide I-S tetrasodium	Carbohydrates
Heparin carbohydrate IS tetrasodium is the major disaccharide produced by heparinases I and II from heparin.

HY-W127440

i-Cholesteryl methyl ether	Drug Delivery
i-Cholesteryl methyl ether is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-NP122

Highly purified Type I collagen, from porcine skin Porcine Type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from porcine skin (Porcine Type I collagen, immunization grade) is an immune grade collagen derived from porcine skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP127

Highly purified Type I collagen, from canine skin Canine Type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from canine skin (Canine Type I collagen, immunization grade) is an immune grade collagen derived from canine skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP107

Highly purified Type I collagen, from rat skin Rat Type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from rat skin (Rat Type I collagen, immunization grade) is an immune grade collagen derived from rat skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP109

Highly purified type I collagen, from mouse skin Mouse Type I collagen, immunization grade	Native Proteins
Highly purified type I collagen, from mouse skin (Mouse Type I collagen, immunization grade) is an immune grade collagen derived from mouse skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP112

Highly purified Type I collagen, from chick skin Chick type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from chick skin (Chick type I collagen, immunization grade) is an immune grade collagen derived from chick skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP128

Highly purified Type I collagen, from rabbit skin Rabbit Type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from rabbit skin (Canine Type I collagen, immunization grade) is an immune grade collagen derived from rabbit skin, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-NP116

Highly purified Type I collagen, from human placenta Human Type I collagen, immunization grade	Native Proteins
Highly purified Type I collagen, from human placenta (Human Type I collagen, immunization grade) is an immune grade collagen derived from human placenta, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-167556

C.I.Direct Blue 199	Cell Assay Reagents
C.I.Direct Blue 199 is a kind of biochemical reagent.

HY-Y0961

Cuprous iodide Copper(I) iodide	Biochemical Assay Reagents
Cuprous iodide (Copper(I) iodide) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-158225

Methacrylated Type I collagen

Col1MA

3D Bioprinting

Methacrylated Type I collagen (Col1MA) is a methacrylated tissue engineering scaffold material. Methacrylated Type I collagen retains the essential properties of natural collagen, including spontaneous fiber self-assembly and enzymatic biodegradability. Methacrylated Type I collagen is capable of self-assembly into fibrous hydrogels, intrinsic support of tissue cells through bioactive adhesion sites, and its biodegradability. After photo-cross-linking CMA, the cell viability of encapsulated mesenchymal stem cells was protected .

HY-A0104B

HPMC (Type I,Viscosity:100mPa.s) Hypromellose (Type I,Viscosity:100mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:100mPa.s); Celacol HPM 5000 (Type I,Viscosity:100mPa.s)	Thickeners
Hypromellose (Type I,Viscosity:100mPa.s) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-A0104A

HPMC (Type I,Viscosity:30mPa.s) Hypromellose (Type I,Viscosity:30mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:30mPa.s); Celacol HPM 5000 (Type I,Viscosity:30mPa.s)	Thickeners
Hydroxypropylmethylcellulose (Type I,Viscosity:30mPa.s) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-A0104D

HPMC (Type I,Viscosity:4000mPa.s) Hypromellose (Type I,Viscosity:4000mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:4000mPa.s); Celacol HPM 5000 (Type I,Viscosity:4000mPa.s)	Thickeners
Hydroxypropylmethylcellulose (Type I,Viscosity:4000mPa.s) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-A0104C

HPMC (Type I,Viscosity:400mPa.s) Hypromellose (Type I,Viscosity:400mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:400mPa.s); Celacol HPM 5000 (Type I,Viscosity:400mPa.s)	Thickeners
Hydroxypropylmethylcellulose (Type I,Viscosity:400mPa.s) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-P2738

Collagen, Type I, from bovine achilles tendon Collagen, Type I, substrate for collagenase	Native Proteins
Collagen, Type I, from bovine achilles tendon are extracellular matrix proteins and show many applications in food, cosmetic, pharmaceutical and biomedical industries. Collagens play an important role in the structure and function of skin, cartilage, bone and connective tissue .

HY-W344938

C.I. Acid yellow 3 Quinoline yellow	Indicators
C.I. Acid yellow 3 is an anionic quinolinone dye that is commonly used as a food additive, but also in the cosmetic and pharmaceutical industries .

HY-163970

Heparin disaccharide I-A sodium

Carbohydrates

Heparin disaccharide I-A (sodium)is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

HY-10583G

Y-27632 dihydrochloride (GMP)	Biochemical Assay Reagents
Y-27632 dihydrochloride (GMP) is the GMP level of Y-27632 dihydrochloride (HY-10583). GMP guidelines are used to produce Y-27632 dihydrochloride (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. Y-27632 dihydrochloride is an orally active and ATP-competitive ROCK (Rho-kinase) inhibitor with antiepileptic effect .

HY-113066C

Guanosine 5'-diphosphate (sodium), 96% (HPLC)

2 Publications Verification

GDP (sodium), Type I, 96% (HPLC)

Gene Sequencing and Synthesis

Guanosine 5'-diphosphate (sodium), 96% (HPLC) is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K ⁺ channel. Guanosine 5'-diphosphate sodium, Type I, 96% (HPLC) is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulates the interleukin-6 (IL-6)/stat-3 pathway. Guanosine 5'-diphosphate (sodium), 96% (HPLC) can be used in the research of inflammation, such as anemia of inflammation (AI) .

HY-109506

DPPC 5 Publications Verification 129Y83	Drug Delivery
DPPC (129Y83) is a phosphoglyceride that can be used to prepare lipid monolayers, bilayers, and liposomes. DPPC is the main lipid component of pulmonary surfactant. Dppc-liposome can be effectively used as a delivery vector to induce an immune response against GSL antigen in mice .

HY-161559

Sudan I/OVA	Biochemical Assay Reagents

Cat. No.	Product Name	Target	Research Area

HY-P10440

Cdk5i peptide	CDK	Neurological Disease
Cdk5i peptide is a 12-amino acid peptide fragment derived from Cdk5. Cdk5i peptide is an inhibitor of Cdk5 peptide. Cdk5i peptide can be used in the stud y of neurodegenerative diseases .

HY-P1183

Locustatachykinin I	Peptides	Neurological Disease Endocrinology
Locustatachykinin I is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I is also a substrate for a deamidase .

HY-P1032F

Biotinyl-Angiotensin I (human, mouse, rat)	Endogenous Metabolite	Endocrinology
Biotinyl-Angiotensin I (human, mouse, rat) is biotin-labeled Angiotensin I . Angiotensin I (human, mouse, rat) is the precursor to the vasoconstrictor peptide angiotensin II, cleaved by the angiotensin-converting enzyme (ACE) .

HY-P5798

Fasciculin-I FAS-I	Cholinesterase (ChE)	Neurological Disease
Fasciculin-I is isolated from the mambas venom. Fasciculin-I exerts its toxic effects by inhibiting acetylcholinesterase (AChE). Fasciculin-I blocks α-neurotoxins of nicotinic acetylcholine receptors and cardiac toxins that interact with cell membranes .

HY-P5179

Huwentoxin I HWTX-I	Calcium Channel Sodium Channel	Neurological Disease
Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels. Huwentoxin I inhibits sodium channels in rat hippocampus and cockroach dorsal unpaired median (DUM) neurons with IC₅₀ values of 66.1 and 4.80 nM, respectively .

HY-P3055

Dendrotoxin-I DTX-I	Potassium Channel	Neurological Disease Cancer
Dendrotoxin-I (DTX-I) is a potent K ⁺ channels blocker with IC₅₀s of 0.13-50 nM for voltage-gated potassium channel subunits K_V1.1, K_V1.2 and K_V1.6, respectively. Dendrotoxin-I, a neurotoxin, has the potential for cancer research .

HY-P3446A

Big Gastrin I (human) (TFA)	Peptides	Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Big Gastrin I, human (TFA) is a gastrointestinal hormone consisting of 34 amino acids. Big Gastrin I, human (TFA) can be used as a potential substance for the study of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurological diseases or cardiovascular diseases .

HY-P1768

Urechistachykinin I Uru-TK I	Bacterial	Infection
Urechistachykinin I (Uru-TK I), an invertebrate tachykinin-related peptides (TRPs) isolated from echiuroid worms, shows antimicrobial activities without a hemolytic effect .

HY-P5650

Bombolitin I	Peptides	Infection
Bombolitin I is an antimicrobial peptide derived from bumblebee venom. Bombolitin I can lysate erythrocyte and liposome .

HY-P3053

Helospectin I	Peptides	Cardiovascular Disease
Helospectin I is a neuropeptide of the vasoactive intestinal peptide (VIP) family. Helospectin I has vasodilatory and antihypertensive activities, and decreases blood pressure. Helospectin I is originally isolated from the salivary gland venom of the lizard Heloderma suspectum .

HY-P3055A

Dendrotoxin-I TFA DTX-I TFA	Potassium Channel	Cancer
Dendrotoxin-I (DTX-I) TFA is a potent K ⁺ channel blocker with IC₅₀s of 0.13-50 nM for voltage-gated potassium channel subunits K_V1.1, K_V1.2 and K_V1.6. Dendrotoxin-I TFA, a neurotoxin, has the potential for cancer research .

HY-P1777

IGF-I (24-41) Insulin-like Growth Factor I (24-41)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development .

HY-P3636

Cockroach Myoactive Peptide I Pea-CAH-I	Peptides	Neurological Disease
Cockroach Myoactive Peptide I (Pea-CAH-I) is a cockroach neuropeptide, a member of the adipokinetic hormone/red pigment-concentrating hormone family (AKH/RPCH family) .

HY-P2632A

RAD16-I hydrochloride	Peptides	Neurological Disease
RAD16-I hydrochloride, a soft nanofibrous self-assembling peptide, is a suitable microenvironment for human mesenchymal stem cells’ (hMSC) proliferation and differentiation into chondrocytes . RAD16-I is a well-studied ionic complementary peptide was used as a model to check potential amyloid-like staining properties of SAPNFs .

HY-P2632

RAD16-I	Peptides	Neurological Disease
RAD16-I, a soft nanofibrous self-assembling peptide, is a suitable microenvironment for human mesenchymal stem cells’ (hMSC) proliferation and differentiation into chondrocytes . RAD16-I is a well-studied ionic complementary peptide was used as a model to check potential amyloid-like staining properties of SAPNFs .

HY-P1183A

Locustatachykinin I TFA	Peptides	Neurological Disease Endocrinology
Locustatachykinin I TFA is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I TFA exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I TFA is also a substrate for a deamidase .

HY-P1773

IGF-I (30-41) Insulin-like Growth Factor I (30-41)	Peptides	Metabolic Disease Inflammation/Immunology
IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .

HY-P3545

5-Valine-angiotensin I	Peptides	Cardiovascular Disease
5-Valine-angiotensin I is an Ang I peptide belonging to angiotensin I. 5-Valine-angiotensin I induces muscle contraction, can be used for renin-angiotensin system studies. Angiotensin I is a putative neurotransmitter, is the precursor of angiotensin II and of angiotensin fragment 1-7, which are involved in regulation of fluid volume and the release of aldosterone .

HY-P5156

BDS-I	Potassium Channel	Neurological Disease
BDS-I known as blood depressing substance, is a marine toxin which can be extracted from Anemonia sulcata. BDS-I is a specific inhibitor of Potassium Channel, targeting to Kv3.4. BDS-I inhibits Aβ1-42-induced enhancement of KV3.4 activity, caspase-3 activation, and abnormal nuclear morphology of NGF-differentiated PC-12 cells. BDS-I reverts the Aβ peptide-induced cell death .

HY-P10282

Synapsin I-(3-13)	CaMK	Neurological Disease
Synapsin I-(3-13), a substrate for CaMK1, is a glycoprotein. Synapsin I is a phosphoprotein that coats the cytoplasmic side of synaptic vesicles and regulates their trafficking within nerve terminals .

HY-P1777A

IGF-I (24-41) (TFA) Insulin-like Growth Factor I (24-41) (TFA)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) TFA is amino acids 24 to 41 fragment of IGF-I. IGF-I TFA, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I TFA is partly responsible for systemic growth hormone (GH) activities. IGF-I TFA has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) TFA regulates somatic growth and behavioral development .

HY-P2218

Anditixafortide	Radionuclide-Drug Conjugates (RDCs) Peptides	Cancer
Anditixafortide (Pentixather) is an endoradiotherapeutic vector. Anditixafortide is a CXCR4-targeting peptide derivative .

HY-P1773A

IGF-I (30-41) (TFA) Insulin-like Growth Factor I (30-41) (TFA)	IGF-1R	Metabolic Disease Inflammation/Immunology
IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions) .

HY-P1631

Polyphemusin I	Bacterial	Infection
Polyphemusin I is a natural antimicrobial peptide with excellent antimicrobial activity against Gram-negative and Gram-positive bacteria. Polyphemusin I contains 18 amino acids and is stabilized into an amphiphilic, antiparallel β-hairpin by two disulfide bridges .

HY-P1632

Tachyplesin I	Bacterial	Infection Cancer
Tachyplesin I is a β-hairpin antimicrobial peptide that contains 17 amino acid residues. Tachyplesin I exhibits cytotoxic properties against various human tumor cell lines acting primarily by impairing the integrity of the outer cell membrane .

HY-N2466A

Melanotan I acetate MT-I acetate; [Nle4,D-Phe7]-α-MSH acetate	Melanocortin Receptor	Cancer
Melanotan I acetate is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I acetate is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I acetate can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I acetate can be used for sunlight-induced skin cancers research .

HY-P1806

Gastrin I (1-14), human	Peptides	Metabolic Disease Endocrinology
Gastrin I (1-14), human is 1-14 fragment of human gastrin I peptide. Gastrin I is an endogenous, gastrointestinal peptide hormone. Gastrin is the major hormonal regulator of gastric acid secretion .

HY-P3199

PKCβII Peptide Inhibitor I	PKC	Inflammation/Immunology
PKCβII Peptide Inhibitor I is a PKCβII inhibitor. PKCβII Peptide Inhibitor I shows cardioprotective effects in rat cardiac Ischemia/reperfusion injury model. PKCβII Peptide Inhibitor I also prevents vascular endothelial dysfunction .

HY-115431

Antho-rwamide I	Peptides	Neurological Disease
Antho-rwamide I is a neuropeptide that can be isolated from the sea anemone Anthopleura elegantissima. Antho-rwamide I is resistant to nonspecific aminopeptidases, which increases the stability of the peptide after neuronal release .

HY-N2466

Melanotan I 1 Publications Verification MT-I; [Nle4,D-Phe7]-α-MSH	Melanocortin Receptor	Neurological Disease Cancer
Melanotan I is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I can be used for the research of sun-induced skin cancer, melanoma, inflammation and male erectile dysfunction .

HY-P3934

HIV Protease Substrate I	HIV Protease	Infection
HIV Protease Substrate I is a chromogenic substrate of HIV-1 protease. HIV Protease Substrate I has the cleavage site of HIV protease .

HY-P2200

Siamycin I BMY-29304	HIV Antibiotic	Infection Inflammation/Immunology
Siamycin I (BMY-29304), a 21-residue tricyclic peptide, is a secondary metabolite in actinomycetes. Siamycin I is a HIV fusion inhibitor with ED₅₀s of 0.05 to 5.7 μM for acute HIV type 1 (HIV-1) and HIV-2 infections. Siamycin I inhibits the gelatinase and gelatinase biosynthesis-activating pheromone (GBAP) signaling via the FsrC-FsrA two-component regulatory system in a noncompetitive manner. Siamycin I suppresses the expression of both fsrBDC and gelE-sprE transcripts. Siamycin I, a lasso peptide, interacts with lipid II and inhibits cell wall biosynthesis. Siamycin I, an antibiotic, has the potential for enterococcal infections research .

HY-P1542

Urotensin I Catostomus urotensin I	CRFR	Cardiovascular Disease Endocrinology
Urotensin I (Catostomus urotensin I), a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC₅₀s of 11.46, 9.36 and 9.85 for human CRF₁, human CRF₂ and rat CRF_2α receptors in CHO cells, and K_is of 0.4, 1.8, and 5.7 nM for hCRF₁, rCRF_2α and mCRF_2β receptors, respectively .

HY-P1912

Alpha 1(I) Collagen (614-639), human	MMP	Endocrinology
Alpha 1(I) Collagen (614-639), human is a peptide fragment of alpha-1 type I collagen.

HY-P1396

GRK2i	G Protein-coupled Receptor Kinase (GRK)	Others
GRK2i is a Gβγ-inhibitory peptide that selectively prevents Gβγ-mediated signaling. GRK2i corresponds to the Gβγ-binding domain of GRK2 (G-protein-coupled receptor kinase 2) .

HY-P2492

Renin FRET Substrate I	Peptides	Metabolic Disease
Renin FRET Substrate I is a substrate of human renin. Renin FRET Substrate I is designed to incorporate the renin cleavage site that occurs in the N-terminal peptide of human angiotensinogen .

HY-P1839

Angiotensin I/II (1-5)	Angiotensin Receptor	Cardiovascular Disease
Angiotensin I/II 1-5 is a peptide that contains the amino acids 1-5, which is converted from Angiotensin I/II. Angiotensin I is formed by the action of renin on angiotensinogen. Angiotensin II is produced from angiotensin I. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy .

HY-P1806A

Gastrin I (1-14), human TFA	Peptides	Metabolic Disease Endocrinology
Gastrin I (1-14), human TFA is 1-14 fragment of human gastrin I peptide. Gastrin I is an endogenous, gastrointestinal peptide hormone. Gastrin is the major hormonal regulator of gastric acid secretion .

HY-P5427

EAC3I	Peptides	Others
EAC3I is a biological active peptide. (The autocamtide-3 derived inhibitory peptide (EAC3I) sequence (KKALHRQEAVDAL) mimics the autoinhibitory region of the CaMKII regulatory domain (residues 278–290) and acts by competitively binding to the catalytic site.)

HY-P1194

Spantide I	Neurokinin Receptor	Inflammation/Immunology
Spantide I, a substance P analog, is a selective NK₁ receptor antagonist, with K_i values of 230 nM and 8150 nM for NK₁ and NK₂ receptor, respectively. Spantide I provides an approach to reduce type 1 and enhance the type 2 cytokine IL-10 in the infected cornea, leading to a significant reduction in corneal perforation .

HY-P5282

ApoA-I mimetic peptide	Peptides	Others
ApoA-I mimetic peptide (PVLDLFRELLNELLEALKQKLK) has good lecithin:cholesterol acyl transferase (LCAT) activation potency. ApoA-I mimetic peptide can be used for synthesis of peptide/lipid complex .

HY-P1829

Angiotensin I/II (1-6)	Angiotensin Receptor	Cardiovascular Disease
Angiotensin I/II 1-6 contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. The precursor angiotensinogen is cleaved by renin to form angiotensin I. Angiotensin I ishydrolyzed by angiotensin-converting enzyme (ACE) to form the biologically active angiotensin II. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy .

HY-P10599

Scyliorhinin I	Neurokinin Receptor	Neurological Disease
Scyliorhinin I is a tachykinin-1 (NK-1) and tachykinin-2 (NK-2) receptor agonist with a K_i value of 0.9 nM for rat submandibular gland NK-1 receptor and 2 nM for hamster bladder NK-2 receptor. Scyliorhinin I has the ability to contract the longitudinal muscles of the guinea pig ileum .

HY-P10551

Apo A-I mimetic 5A peptide	Peptides	Cardiovascular Disease
Apo A-I mimetic 5A peptide is a synthetic peptide molecule designed based on the structure and function of naturally occurring apolipoprotein A-I (Apo A-I). Apo A-I mimetic 5A peptide can promote the efflux of cholesterol from cells and help reduce the accumulation of cholesterol in cells. Apo A-I mimetic 5A peptide also shows anti-inflammatory activity and can reduce inflammatory markers in blood and tissues. Apo A-I mimetic 5A peptide can be used in the study of cardiovascular diseases .

HY-P1194B

[D-Pro2] Spantide I TFA	Neurokinin Receptor	Neurological Disease
[D-Pro2] Spantide I TFA is a Spantide analog. Spantide I is a selective NK1 receptor antagonist .

HY-P1839A

Angiotensin I/II (1-5) (TFA)	Angiotensin Receptor	Cardiovascular Disease
Angiotensin I/II 1-5 TFA is a peptide that contains the amino acids 1-5, which is converted from Angiotensin I/II. Angiotensin I is formed by the action of renin on angiotensinogen. Angiotensin II is produced from angiotensin I. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy .

HY-125295

Leucokinin I	Peptides	Others
Leucokinin I is a peptide that stimulates contraction of the anterior midgut and hindgut muscles involved in feeding in Rhodnius prolixus but not absorption in the anterior midgut .

HY-P1396A

GRK2i TFA	G Protein-coupled Receptor Kinase (GRK)	Others
GRK2i TFA is a GRK2 inhibitory polypeptide that specifically inhibits Gβγ activation of GRK2. GRK2i TFA corresponds to the Gβγ-binding domain and acts as a cellular Gβγ antagonist .

HY-P1073

ProTx-I	Calcium Channel Sodium Channel Potassium Channel	Cancer
ProTx-I, a venom toxin of the tarantula Thrixopelma pruriens, is a potent, selective Ca_V3.1 channel blocker with IC₅₀ values of 0.2 μM and 31.8 μM for hCa_V3.1 and hCa_V3.2 respectively. ProTx-I is also a potent blocker for voltage-gated Na ⁺ channels and inhibits K_V 2.1 channels .

HY-W008867

Fmoc-Tyr(3,5-I2)-OH	Amino Acid Derivatives	Others
Fmoc-Tyr(3,5-I2)-OH is a tyrosine derivative .

Cat. No.	Product Name

HY-KE7010

Cla I
MCE Cla I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: BspD I, Bsa29 I, BseC I, Bsu15 I, BsuTU I.

HY-KE7047

Age I
Age I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: AsiG I, CspA I, BshT I, PinA I.

HY-KE7013

Eag I
MCE Eag I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: BseX3 I, BstZ I, EclX I, Eco52 I.

HY-KE7012

Dpn II
MCE Dpn II is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Mbo I, Sau3A I, Bsp143 I, BstMB I, Nde II, BstKT I.

HY-KE7046

Nru I
Nru I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Bsp68 I, BtuM I, Rru I.

HY-KE7008

BstB I
MCE BstB I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Asu II, Bpu14 I, Bsp119 I, BspT104 I, Nsp V, Sfu I.

HY-KE7050

BsmB I
BsmB I is one of the endonucleases of Type IIs that recognize non-palindromic sequences and cut outside of the recognition sequence, and is commonly used in Golden Gate assembly. Isoschizomers: Esp3 I, BstGZ53 I, Esp16 I, Esp23 I.

HY-KE7045

Xho I
Xho I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: PaeR7 I, Sfr274 I, Sla I.

HY-KE7042

Stu I
MCE Stu I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Eco147 I, Pce I, SseB I.

HY-KE7007

Bsa I
MCE Bsa I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Eco31 I, Bso31 I, BspTN I.

HY-KE7029

Nsi I
MCE Nsi I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: EcoT22 I, Mph1103 I, Zsp2 I.

HY-KE7052

BsmB I, ADCF
BsmB I, ADCF is animal derived component free, and has good redundancy of enzyme activity, which can easily cope with excessive substrate or difficult template enzyme cutting. Isoschizomers: Esp3 I, BstGZ53 I, Esp16 I, Esp23 I.

HY-KE7009

BstE II
MCE BstE II is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: BstP I, Eco91 I, EcoO65 I, PspE I.

HY-KE7048

BspQ I
BspQ I is one of the endonucleases of Type IIs that recognize non-palindromic sequences and cut outside of the recognition sequence, and is commonly used in Golden Gate assembly. Isoschizomers: Sap I, Lgu I, PciS I.

HY-KE7034

Sac II
MCE Sac II is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Cfr42 I, Ksp I, Sfr303 I, SgrB I.

HY-KE7033

Sac I
MCE Sac I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Psp124B I, Sst I, Ecl136 II, EcoICR I.

HY-KE7003

Asc I
MCE Asc I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: PalA I, Sgs I.

HY-KE7039

Spe I
MCE Spe I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Ahl I, Bcu I.

HY-KE7001

ApaL I
MCE ApaL I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Alw44 I, Vne I.

HY-KE7005

Bcl I
MCE Bcl I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Fba I, Ksp22 I.

HY-KE7017

Fsp I
MCE Fsp I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Acc16 I，Nsb I.

HY-KE7036

Sbf I
MCE Sbf I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Sda I, Sse8387 I.

HY-KE7038

Sma I
MCE Sma I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Cfr9 I, Xma I.

HY-KE7022

Kpn I
MCE Kpn I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Asp718 I, Acc65 I.

HY-KE7002

Avr II
MCE Avr II is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: AspA2 I, Bln I, XmaJ I.

HY-KE7028

Not I
MCE Not I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: CciN I.

HY-KE7011

Dpn I
MCE Dpn I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Mal I.

HY-KE7020

Hpa I
MCE Hpa I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: KspA I.

HY-KE7026

Nde I
MCE Nde I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: FauND I.

HY-KE7027

Nhe I
MCE Nhe I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Bmt I.

HY-KE7031

Pst I
MCE Pst I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: BspMA I.

HY-KE7040

Sph I
MCE Sph I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Pae I.

HY-KE7016

Esp3 I
MCE Esp3 I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: BsmB I.

HY-KE7025

Nco I
MCE Nco I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Bsp19 I.

HY-KE7043

Taq I
Taq I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.

HY-KE7044

Xba I
Xba I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.

HY-KE8010

Exonuclease I
This product is obtained by expressing the Exo I gene (E. coli) in Escherichia coli and then purifying and isolating it multiple times.

HY-KE7004

BamH I
MCE BamH I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.

HY-KE7019

Hinf I
MCE Hinf I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.

HY-KE7024

Mnl I
MCE Mnl I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.

HY-KE7023

Mlu I
MCE Mlu I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.

HY-KE7030

Pac I
MCE Pac I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.

HY-KE7035

Sal I
MCE Sal I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.

HY-KE7037

Sfi I
MCE Sfi I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.

HY-KE7041

Ssp I
MCE Ssp I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products.

HY-KE8007

DNA Polymerase I(E.coli)
This product is a DNA polymerase obtained by expressing DNA Polymerase I (E. coli) in E. coli and purifying and isolating it multiple times.

HY-KE7014

EcoR I
MCE EcoR I is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Fun II.

HY-KE7049

Sge I
Sge I restriction enzyme recognizes and cleaves DNA targets containing 5-methylcytosine on one or both DNA strands, and cuts best at 37℃.

HY-KE7015

EcoR V
MCE EcoR V is a restriction enzyme for rapid DNA digestion, including plasmid, genomic DNA as well as PCR products. Isoschizomers: Eco32 I.

HY-K1004

SYBR Green I Nucleic Acid Gel Stain 5+ Cited Publications
MCE SYBR Green I Nucleic Acid Gel Stain is one of the most sensitive stains available for detecting double-stranded DNA (dsDNA) in agarose and polyacrylamide gels.

Cat. No.	Product Name	Target	Research Area

HY-P990188

Anti-Mouse MHC class II (I-A) Antibody (Y-3P)	Inhibitory Antibodies	Others
Anti-Mouse MHC class II (I-A) Antibody (Y-3P) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse MHC class II.

HY-P990186

Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2)	Inhibitory Antibodies	Others
Anti-Mouse MHC Class II (I-Ak, I-Ar, I-Af, I-As,I-Ag7) Antibody (10-3.6.2) is a mouse-derived IgG2c, κ type antibody inhibitor, targeting to mouse MHC Class II.

HY-P990187

Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114)	Inhibitory Antibodies	Others
Anti-Mouse MHC Class II (I-A/I-E) Antibody (M5/114) is a rat-derived IgG2b type antibody inhibitor, targeting to mouse MHC Class II.

HY-P990832

Anti-MHC Class I Antibody (W6/32)	Inhibitory Antibodies	Others
Anti-MHC Class I Antibody (W6/32) is a kind of mouse IgG2a,?κ chimeric antibody, targeting to human MHC Class I. The recommend isotype control of Anti-MHC Class I Antibody (W6/32): Mouse IgG2a kappa, Isotype Control (HY-P99978).

HY-P990190

Anti-Swine MHC Class I (SLAd) Antibody (74-11-10)	Inhibitory Antibodies	Others
Anti-Swine MHC Class I (SLAd) Antibody (74-11-10) is a mouse-derived IgG2b, κ type antibody inhibitor, targeting to Swine MHC Class I.

HY-P990251

Anti-Human/Mouse denatured collagen type-I Antibody (XL313)	MMP	Others
Anti-Human/Mouse denatured collagen type-I Antibody (XL313) is a mouse-derived IgG1, κ type antibody inhibitor, targeting to human/mouse denatured collagen type-I.

HY-P99619

Finotonlimab SCT-I10A	PD-1/PD-L1	Cancer
Finotonlimab (SCT-I10A) is a recombinant humanised IgG PD-1 antibody. Finotonlimab has the potential for solid tumors or lymphomas research .

HY-P990194

Anti-Mouse MHC Class I (H-2Kd) Antibody (HB-159))	Inhibitory Antibodies	Others
Anti-Mouse MHC Class I (H-2Kd) Antibody (HB-159)) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse MHC Class I.

HY-P990192

Anti-Mouse MHC Class I (H-2Kk) Antibody (AF3-12.1.3)	Inhibitory Antibodies	Others
Anti-Mouse MHC Class I (H-2Kk) Antibody (AF3-12.1.3) is a mouse-derived IgG1 type antibody inhibitor, targeting to mouse MHC Class I.

HY-P990195

Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8)	Inhibitory Antibodies	Others
Anti-Mouse MHC Class I (H-2) Antibody (M1/42.3.9.8) is a rat-derived IgG2a, κ type antibody inhibitor, targeting to mouse MHC Class I.

HY-P99993

Human IgG1 (S239D/I332E) kappa, Isotype Control	Inhibitory Antibodies	Inflammation/Immunology
Human IgG1 (S239D/I332E) kappa, Isotype Control, a human-mouse chimeric monoclonal antibody, is an isotype control for Human IgG1 (S239D/I332E)κ antibody.

HY-P990193

Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Antibody (34-1-2S)	Inhibitory Antibodies	Others
Anti-Mouse MHC Class I (H-2Kd, H-2Dd) Antibody (34-1-2S) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse MHC Class I.

HY-P990191

Anti-Mouse MHC Class I (H-2Kk, H-2Dk) Antibody (15-3-1S (HB-13))	Inhibitory Antibodies	Others
Anti-Mouse MHC Class I (H-2Kk, H-2Dk) Antibody (15-3-1S (HB-13)) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse MHC Class I.

HY-P990813

Anti-Mouse Nonclassical MHC Class I molecule Qa-1b Antibody (4C2.4A7.5H11)	Inhibitory Antibodies	Others
Anti-Mouse Nonclassical MHC Class I molecule Qa-1b Antibody (4C2.4A7.5H11) is a kind of mouse IgG1 in vivo mouse antibody, targeting to Nonclassical MHC Class I molecule Qa-1b. The recommend isotype control of Anti-Mouse Nonclassical MHC Class I molecule Qa-1b Antibody (4C2.4A7.5H11): Mouse IgG1 kappa, Isotype Control (HY-P99977).

HY-P99530

Valanafusp alfa AGT-181; HIRMAb-IDUA	Insulin Receptor	Metabolic Disease
Valanafusp alfa (AGT-181) is a chimeric monoclonal antibody that fuses human α-L-iduronidase (IDUA) and targets the human insulin receptor (HIR). Valanafusp alfa has brain penetrating properties, making it useful for research on mucopolysaccharidosis type I (MPS I) .

HY-P990185

Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S)	Inhibitory Antibodies	Others
Anti-Mouse/Rat MHC Class II (I-Ek/RT1-D) Antibody (14-4-4S) is a mouse-derived IgG2a, κ type antibody inhibitor, targeting to mouse/rat MHC Class II.

HY-P990146

Anti-Mouse/Rat/Human v-H-Ras Antibody (Y13-238)	Inhibitory Antibodies	Others
Anti-Mouse/Rat/Human v-H-Ras Antibody (Y13-238) is a rat-derived IgG2a type antibody inhibitor, targeting to mouse/rat/human v-H-Ras.

HY-P99581

Tabituximab barzuxetan (exclude Y90) OTSA101-DTPA; OTSA101-DTPA-90Y; OTSA101-SS01	Wnt	Cancer
Tabituximab barzuxetan (exclude Y90) is a radioimmunoconjugate composed of a humanized monoclonal antibody targeting FZD-10 (OTSA-101). Tabituximab barzuxetan shows antineoplastic activity. Tabituximab barzuxetan can be used for synovial sarcoma research .

HY-P99694

Lepunafusp alfa JR-171	Inhibitory Antibodies	Neurological Disease
Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I .

HY-P99168

Anifrolumab 1 Publications Verification	Inhibitory Antibodies	Inflammation/Immunology
Anifrolumab is a type I interferon (IFN) receptor antagonist, a human monoclonal antibody. Anifrolumab blocks the activity of type I interferon. Anifrolumab can be used in systemic lupus erythematosus (SLE) research .

HY-164152

ADC Control Human IgG1-Deruxtecan (DAR 4)	Antibody-Drug Conjugates (ADCs) Topoisomerase	Cancer
ADC Control Human IgG1-Deruxtecan (DAR 4) is a humanized monoclonal antibody that is an isotype control of ADC human IgG1-Deruxtecan and can inhibit DNA topoisomerase I. The antibody portion is Human IgG1 kappa, Isotype Control (HY-P99001), and the drug-linker conjugate for ADC is Deruxtecan (HY-13631E) .

HY-P990061

Polzastobart JTX 8064	Inhibitory Antibodies	Inflammation/Immunology Cancer
Polzastobart (JTX-8064) is a humanized IgG4 monoclonal antagonist antibody that selectively binds LILRB2 and prevents it from binding its ligands, classical and non-classical MHC I molecules. Polzastobart enhances pro-inflammatory cytokine production in macrophages by blocking the ability of LILRB2 to bind HLA-A/B and/or HLA-G, a marker of immunotolerance on cancer cells. Polzastobart is a macrophage immune checkpoint inhibitor .

HY-P99509

Zelminemab AMG-301	Adenylate Cyclase	Neurological Disease
Zelminemab (AMG-301) is a humanized monoclonal antibody that inhibits PACAP type I (PAC1) receptor .

HY-P9913

Rituximab Maximum Cited Publications 6 Publications Verification Anti-Human CD20 type I, Chimeric Antibody	Radionuclide-Drug Conjugates (RDCs) CD20	Inflammation/Immunology Cancer
Rituximab is an anti-CD20 chimeric monoclonal antibody used for research of certain autoimmune diseases and cancer.

HY-P99359

Elezanumab ABT-555; AE12-1Y-QL; Anti-RGMA Reference Antibody (elezanumab)	TGF-beta/Smad	Metabolic Disease
Elezanumab (ABT-555; AE12-1Y-QL) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway, with an IC₅₀ around 97 pM. Elezanumab promotes neuroregeneration and neuroprotection in neuronal injury and demyelination models binds N-terminal RGMa, blocks BMP signaling and lacks RGMc cross-reactivity. elezanumab has neuroregenerative and neuroprotective activities without impact on iron metabolism .

HY-P99478

Bifarcept	IFNAR	Inflammation/Immunology
Bifarcept is a recombinant antibody of interferon receptor type I (IFN-RI). Bifarcept can bind IFN-β and prolong its serum half-life .

HY-P99813

Patritumab deruxtecan HER3-DXd; U3-1402	Antibody-Drug Conjugates (ADCs)	Cancer
Patritumab deruxtecan (HER3-DXd) is an antibody-drug conjugate (ADC) consisting of a fully human anti-HER3 IgG1 monoclonal antibody Patritumab (HY-P99275) attached to a topoisomerase I inhibitor payload via a tetrapeptide-based cleavable linker. Patritumab deruxtecan shows anticancer activity .

HY-P99843

Datopotamab	TROP2 ADC Antibody	Cancer
Datopotamab (CDP7657) is a humanized anti trophoblast cell surface antigen 2 (TROP2) antibody. Datopotamab can generate antibody drug conjugates (ADC) (HY-141598) with DNA topoisomerase I inhibitor Deruxtecan (HY-13631E). Datopotamab can be used in the study of triple negative breast cancer and non-small cell lung cancer .

HY-P99135

Anti-Mouse H-2K Antibody (Y-3)	Inhibitory Antibodies	Inflammation/Immunology
Anti-Mouse H-2K Antibody is an anti-mouse H-2K IgG2b antibody inhibitor derived from host mouse.

HY-P99008

Atibuclimab 1 Publications Verification	Inhibitory Antibodies	Inflammation/Immunology
Atibuclimab, is a chimeric monoclonal antibody directed against CD14 and is composed of murine variable and human IgG4 Fc regions. Atibuclimab can be used for the research of amyotrophic lateral sclerosis . Atibuclimab attenuates LPS-induced symptoms and strongly inhibits LPS-induced proinflammatory cytokine release, while only delaying the release of the anti-inflammatory cytokines soluble TNF receptor type I and IL-1 receptor antagonist .

HY-P99625

Frexalimab SAR441344; INX-021	TNF Receptor	Inflammation/Immunology
Frexalimab (SAR441344) is a second-generation monoclonal antibody targeting the CD40 ligand (CD40L) with a good safety profile. Frexalimab inhibits the binding between CD40 and CD40L to modulate immune response. Frexalimab is likely to help prevent the process of β-cell destruction. Frexalimab is proming for multiple sclerosis, lupus erythematosus, Sjögren’s syndrome and type I diabetes research .

HY-P990680

Anti-Mouse CD40 Antibody (FGK4.5/FGK45)	Inhibitory Antibodies	Inflammation/Immunology
Anti-Mouse CD40 Antibody (FGK4.5/FGK45) is a rat-derived IgG2a monoclonal antibody targeting mouse CD40. CD40 is a type I transmembrane glycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD40 can act as a co-stimulatory molecule to activate B cells, dendritic cells, monocytes, and other APCs, promoting anti-tumor T cell responses.

HY-P99171

Gevokizumab	Interleukin Related	Inflammation/Immunology Cancer
Gevokizumab is a potent anti-IL-1β antibody, negatively modulates IL-1β signaling through an allosteric mechanism. Gevokizumab selectively decreases the binding affinity of IL-1β for the IL-1 receptor type I (IL-1RI) signaling receptor instead of IL-1 counter-regulatory decoy receptor (IL-1 receptor type II) .

HY-P99666

Interferon alfa	IFNAR	Infection Cancer
Albinterferon alfa-2b is a type I interferon that activates novel genes and exerts potent antiviral and antiproliferative activity on target cells. Signaling by Albinterferon alfa-2b requires receptor-dependent activation of Stat1 and Stat2 to form a heterodimeric STAT that binds to the DNA-binding protein IRF-9 (p48) and forms ISGF-3 (IFN-stimulated gene factor 3). The driver genes are then further activated by ISGF-3 to achieve antiviral function .

HY-P99116

Faricimab RG7716	VEGFR	Cardiovascular Disease Metabolic Disease Inflammation/Immunology
Faricimab, an overall good safety and tolerability profile, is a bispecific antibody targeting Angiopoietin-2 (Ang-2) and vascular endothelial growth factor-A (VEGF-A). Faricimab prevents retinal vascular leakage, cell death and inflammation in retinal ischemia/reperfusion (I/R) injury and sCNV mouse models. Faricimab demonstrates statistically superior visual acuity gains versus Ranibizumab (HY-P9951). Faricimab can be used for retinal diseases, such as age-related macular degeneration (w-AMD), diabetic macular edema (DME) and macular edema following retinal vein occlusion (RVO) .

Species:	Human (259) Porcine (1) Rhesus Macaque (1) Rat (11) Xenopus laevis (1) E.coli (2) Cynomolgus (16) Rabbit (1) Pig (2) Canine (3) Virus (21) Mouse (53) Staphylococcus aureus (2)
Tag:	His (287) SUMO (17) Tag Free (38) Strep (6) Avi (46) Myc (4) GST (26) HA (1) MBP (3) Fc (42) Flag (10)
Source:	HEK293 (199) E. coli Cell-free (6) CHO (3) P. pastoris (13) Sf9 insect cells (48) E. coli (117)

Cat. No.	Compare	Product Name	Species	Source

HY-P75162

	GLO1/Glyoxalase I Protein, Mouse (His) Lactoylglutathione lyase; Glyoxalase I; Glx I	Mouse	E. coli
	GLO1 is an important enzyme responsible for catalyzing the conversion of hemithiol (the product of methylglyoxal and glutathione) to S-lactoylglutathione. This enzyme activity plays a crucial role in cellular detoxification by mitigating the effects of methylglyoxal, a reactive carbonyl species. GLO1/Glyoxalase I Protein, Mouse (His) is the recombinant mouse-derived GLO1/Glyoxalase I protein, expressed by E. coli , with N-His, N-6*His labeled tag. The total length of GLO1/Glyoxalase I Protein, Mouse (His) is 183 a.a., with molecular weight of ~25 & 48 kDa, respectively.

HY-P7526

	Apolipoprotein A-I/APOA1 Protein, Human rHuApolipoprotein A-I; ApoA1; Apolipoprotein A-I	Human	E. coli
	Apolipoprotein A-I/APOA1 Protein is a secreted protein located on the outside of cell membranes and is the main structural apolipoprotein of high-density lipoprotein (HDL), playing a key role in the reverse cholesterol transport pathway. Apolipoprotein A-I/APOA1 protein interacts with the cell surface receptor SR-BI, thereby promoting dengue virus (DV) infection. Apolipoprotein A-I/APOA1 Protein can also activate sperm motility as part of the SPAP complex. Apolipoprotein A-I/APOA1 Protein has anti-inflammatory, anti-atherosclerotic, anti-apoptotic, anti-tumor, and anti-thrombotic functions. Apolipoprotein A-I/APOA1 Protein Protein, Human is made up of 267 amino acids and is expressed in Escherichia coli (E. coli).

HY-P71469

	Cardiac troponin I/Tnni3 Protein, Mouse (His-SUMO) Tnni3; Troponin I; cardiac muscle; Cardiac troponin I	Mouse	E. coli
	Cardiac troponin I, also known as Tnni3, plays a key role as an inhibitory subunit in the troponin complex, a key regulator of calcium sensitivity in actomyosin ATPase activity in striated muscle.Tnni3 interacts with TRIM63, emphasizing its involvement in complex cellular processes.Cardiac troponin I/Tnni3 Protein, Mouse (His-SUMO) is the recombinant mouse-derived Cardiac troponin I/Tnni3 protein, expressed by E.coli , with N-SUMO, N-6*His labeled tag.

HY-P79197

	Heparinase I Protein, B. thetaiotaomicron (His) Heparin lyase I family protein	Others	E. coli
	Heparinase I protein is an enzyme that degrades heparin and heparan sulfate and can modify extracellular matrix components. In addition to degradation, it also releases growth factors that bind to heparin, affecting the extracellular environment. Heparinase I Protein, B. thetaiotaomicron (His) is the recombinant Heparinase I protein, expressed by E. coli , with N-His labeled tag.

HY-P7525

	Apolipoprotein A-I/APOA1 Protein, Human (HEK293, His) 1 Publications Verification rHuApolipoprotein A-I, His; ApoA1; Apolipoprotein A-I	Human	HEK293
	Apolipoprotein A-I Protein, Human (HEK293, His) expresses in HEK293 with a His tag at the N-terminus. Apolipoprotein A-I (ApoA-I), the major protein component in high-density lipoprotein (HDL), plays key roles in the Reverse Cholesterol Transport pathway. Apolipoprotein A-I is associated with dengue virus (DV) particles and enhances virus infection through SR-BI.

HY-P72832

	Apolipoprotein A-I/APOA1 Protein, Human (HEK293, Fc) Apolipoprotein A-I; Apo-AI; ProapoA-I; APOA1	Human	HEK293
	Apolipoprotein AI plays a key role in reverse cholesterol transport, promoting cholesterol efflux from tissues and acting as a cofactor for lecithin cholesterol acyltransferase (LCAT). It forms homodimers and participates in the SPAP complex, which is essential for sperm motility, interacting with both NAXE and CLU. Apolipoprotein A-I/APOA1 Protein, Human (HEK293, Fc) is the recombinant human-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P79244

	Chondroitinase ABC Protein, P. vulgaris (His) Chondroitin sulfate ABC endolyase; Chondroitin ABC endoeliminase; Chondroitin ABC lyase I; Chondroitin sulfate ABC lyase I; ChS ABC lyase I; Chondroitinase ABC I; cABC I; Endochondroitinase ABC; INN: Condoliase	Others	E. coli
	Chondroitinase ABC protein is an endolytic glycosaminoglycan lyase with broad specificity that effectively degrades polysaccharides such as chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, dermatan sulfate, and smaller degree of hyaluronic acid. This enzyme activity is facilitated by β-elimination of the 1,4-hexosamine bond, resulting in unsaturated tetra- and disaccharides. Chondroitinase ABC Protein, P. vulgaris (His) is the recombinant Chondroitinase ABC protein, expressed by E. coli , with N-His, N-6*His labeled tag. The total length of Chondroitinase ABC Protein, P. vulgaris (His) is 997 a.a., with molecular weight of ~110 kDa.

HY-P73136

	IGF-I/IGF-1 Protein, Human (HEK293, hFc) Insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1	Human	HEK293
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (HEK293, hFc) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of IGF-I/IGF-1 Protein, Human (HEK293, hFc) is 70 a.a., with molecular weight of 35-40 kDa.

HY-P700241AF

	Animal-Free IGF-I Protein, Pig (His) Insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1	Pig	E. coli
	The IGF-I protein is structurally similar to insulin and has excellent growth-promoting activity. As a potential physiological regulator, it affects [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Animal-Free IGF-I Protein, Pig (His) is the recombinant pig-derived animal-FreeIGF-I protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IGF-I Protein, Pig (His) is 70 a.a., with molecular weight of ~8.59 kDa.

HY-P74843

	IGF-I/IGF-1 Protein, Mouse (P.pastoris) Insulin-like growth factor I; IGF-I; MGF; Somatomedin-C; IBP1	Mouse	P. pastoris
	IGF-I/IGF-1 Protein, part of the insulin family, is highlighted. IGF-I/IGF-1 Protein, Mouse (P.pastoris) is the recombinant mouse-derived IGF-I/IGF-1 protein, expressed by P. pastoris , with tag free.

HY-P72833

	Apolipoprotein A-I/APOA1 Protein, Mouse (246a.a, HEK293, Fc) Apolipoprotein A-I; Apo-AI; ProapoA-I; APOA1	Mouse	HEK293
	The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (246a.a, HEK293, Fc) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of Apolipoprotein A-I/APOA1 Protein, Mouse (246a.a, HEK293, Fc) is 246 a.a., with molecular weight of ~58 kDa.

HY-P71403

	UBE2I Protein, Human (GST) SUMO-Conjugating Enzyme UBC9; SUMO-Protein Ligase; Ubiquitin Carrier Protein 9; Ubiquitin Carrier Protein I; Ubiquitin-Conjugating Enzyme E2 I; Ubiquitin-Protein Ligase I; p18; UBE2I; UBC9; UBCE9	Human	E. coli
	UBE2I Protein, a key participant in protein sumoylation, accepts ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4, and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex. Teaming up with E3 ligases like RANBP2, CBX4, and ZNF451, UBE2I catalyzes the covalent attachment of these SUMO proteins to target proteins, including critical substrates FOXL2 and KAT5. Its enzymatic activity extends to forming poly-SUMO chains, influencing diverse cellular processes and playing a pivotal role in specific protein modifications, such as sumoylation of p53/TP53 at 'Lys-386' and ERCC6. UBE2I Protein, Human (GST) is the recombinant human-derived UBE2I protein, expressed by E. coli, with N-GST labeled tag. The total length of UBE2I Protein, Human (GST) is 158 a.a., with molecular weight of ~40.0 kDa.

HY-P7070

	IGF-I/IGF-1 Protein, Mouse 5 Publications Verification rMuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I	Mouse	E. coli
	IGF-I/IGF-1 Protein, Mouse is a mitogenic cytokine.

HY-P7203

	IGF-I/IGF-1 Protein, Rat 1 Publications Verification rRtIGF-I; Somatomedin C; IGF1; Mechano growth factor	Rat	E. coli
	IGF-I/IGF-1 Protein, Rat has somatomedin activity and ability to potently promote neuronal survival.

HY-P71543

	DNASE1L3 Protein, Human (GST) Deoxyribonuclease gamma; Deoxyribonuclease I like 3; Deoxyribonuclease I like III; Deoxyribonuclease I-like 3; DHP 2; DHP2; DNAS1L3; DNase gamma; DNase I homolog protein 2; DNase I homolog protein DHP2; DNase I like 3; DNase I-like 3; DNASE1L3; DNSL3_HUMAN; Liver and spleen DNase; LS DNase; LS-DNase; LSD; SLEB 16; SLEB16	Human	E. coli
	DNASE1L3 proteolytically cleaves single- and double-stranded DNA and generates fragments with 3'-OH termini. It can cleave chromatin, nucleosomes, and liposome-coated DNA. DNASE1L3 Protein, Human (GST) is the recombinant human-derived DNASE1L3 protein, expressed by E. coli , with N-GST labeled tag. The total length of DNASE1L3 Protein, Human (GST) is 285 a.a., with molecular weight of ~60.4 kDa.

HY-P703079

	DNASE1L3 Protein, Human (His) Deoxyribonuclease gamma; Deoxyribonuclease I like 3; Deoxyribonuclease I like III; Deoxyribonuclease I-like 3; DHP 2; DHP2; DNAS1L3; DNase gamma; DNase I homolog protein 2; DNase I homolog protein DHP2; DNase I like 3; DNase I-like 3; DNASE1L3; DNSL3_HUMAN; Liver and spleen DNase; LS DNase; LS-DNase; LSD; SLEB 16; SLEB16	Human	E. coli
	DNASE1L3 proteolytically cleaves single- and double-stranded DNA and generates fragments with 3'-OH termini. It can cleave chromatin, nucleosomes, and liposome-coated DNA. DNASE1L3 Protein, Human (His) is the recombinant human-derived DNASE1L3 protein, expressed by E. coli , with C-10*His labeled tag.

HY-P78947

	EXO I Protein, E. coli (His)	E.coli	E. coli
	EXO I Protein, documented with high processivity, degrades single-stranded DNA (ssDNA). It also acts as a DNA deoxyribophosphodiesterase, releasing deoxyribose-phosphate moieties post-cleavage at apurinic/apyrimidinic (AP) sites by AP endonuclease or AP lyase. EXO I's dual functionality in ssDNA degradation and deoxyribose-phosphate removal at AP sites underscores its crucial role in DNA repair processes, maintaining genome integrity. EXO I Protein, E. coli (His) is the recombinant E. coli-derived EXO I protein, expressed by E. coli , with N-6*His labeled tag. EXO I Protein, E. coli (His), has molecular weight of ~54.5 kDa.

HY-P70788

	IGF-I/IGF-1 Protein, Human (G49-A118) 5 Publications Verification Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1	Human	E. coli
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (G49-A118) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by E. coli , with tag free.

HY-P700478

	IGF-I/IGF-1 Protein, Human (P. pastoris, N-His) 1 Publications Verification Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1	Human	P. pastoris
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. IGF-I/IGF-1 Protein, Human (P. pastoris, N-His) is the recombinant human-derived IGF-I/IGF-1 protein, expressed by P. pastoris , with N-6*His labeled tag.

HY-P7018

	IGF-I/IGF-1 Protein, Human (70a.a) Maximum Cited Publications 11 Publications Verification rHuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I	Human	E. coli
	IGF-I/IGF-1 Protein, Human (70a.a) is a mitogenic cytokine, binds to IGF type 1 receptor, and modulates growth in many tissues, such as nervous tissue, lymphoid tissue, reproductive tissue, smooth muscle, endothelium, and bone; IGF-I/IGF-1 Protein also mediates neuroprotective mechanism.

HY-P72974

	DNase I Protein, Human (HEK293, His) 5 Publications Verification Deoxyribonuclease-1; DNase I; Dornase alfa; DNASE1; DNL1; DRNI	Human	HEK293
	The DNase I protein is a serum endonuclease secreted by a variety of exocrine and endocrine organs and expressed in non-hematopoietic tissues. It preferentially selects protein-free DNA, plays a key role in apoptosis-induced cell death, and inhibits actin polymerization by specifically binding to G-actin. DNase I Protein, Human (HEK293, His) is the recombinant human-derived DNase I protein, expressed by HEK293 , with C-His labeled tag. The total length of DNase I Protein, Human (HEK293, His) is 282 a.a., with molecular weight of ~37 kDa.

HY-P70698AF

	Animal-Free IGF-I/IGF-1 Protein, Mouse (His) rMuIGF-1; IGF-IA; Somatamedin C; MGF; IGF-I	Mouse	E. coli
	The IGF-I/IGF-1 protein is structurally similar to insulin and has potent growth-promoting activity. As a physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts, exceeding the efficacy of insulin at lower concentrations. Animal-Free IGF-I/IGF-1 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIGF-I/IGF-1 protein, expressed by E. coli , with C-His labeled tag.

HY-P70783

	LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) 1 Publications Verification Long R3 IGF-I; Insulin-like growth factor I; MGF; Somatomedin-C; IBP1	Human	E. coli
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is the recombinant human-derived LR3 IGF-I/IGF-1 protein, expressed by E. coli , with tag free. and E51R, , , , mutation. The total length of LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is 70 a.a., with molecular weight of ~11.0 kDa.

HY-P72227

	HLA-G Protein, Human (His-SUMO) B2 microglobulin; DADB-15K14.8; HLA 6.0; HLA class I histocompatibility antigen alpha chain G; HLA class I histocompatibility antigen; alpha chain G; HLA class I molecule; HLA G; HLA G antigen; HLA G histocompatibility antigen class I G; HLA G3; HLA-G; HLA-G histocompatibility antigen; class I; HLA60; HLAG; HLAG_HUMAN; Major histocompatibility complex class I G; MHC class I antigen; MHC class I antigen G; MHC G; T-cell A locus; TCA	Human	E. coli
	HLA-G is a nonclassical major histocompatibility class Ib molecule that is critical for immune regulation at the maternal-fetal interface. It cooperates with B2M to form a complex that selectively binds self-peptides to promote maternal-fetal tolerance by interacting with KIR2DL4, LILRB1, and LILRB2 receptors. HLA-G Protein, Human (His-SUMO) is the recombinant human-derived HLA-G protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.

HY-P70783G

	GMP LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) Long R3 IGF-I; Insulin-like growth factor I; MGF; Somatomedin-C; IBP1	Human	E. coli
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. GMP LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is the recombinant human-derived LR3 IGF-I/IGF-1 protein, expressed by E. coli , with tag free. The total length of GMP LR3 IGF-I/IGF-1 Protein, Human (83a.a, E51R) is 70 a.a., with molecular weight of ~11 kDa.

HY-P700093AF

	Animal-Free IGF-I/IGF-1 Protein, Human (His) 1 Publications Verification Somatamedin C; IGF-IA; Insulin-Like Growth Factor I; IGF-I; Mechano Growth Factor; MGF; Somatomedin-C; IGF1; IBP1	Human	E. coli
	The LR3 IGF-I/IGF-1 protein is similar to insulin and has potent growth-promoting activity that exceeds the efficacy of insulin. As a potential physiological regulator, it stimulates glucose transport and glycogen synthesis in osteoblasts even at significantly lower concentrations than insulin. Animal-Free IGF-I/IGF-1 Protein, Human (His) is the recombinant human-derived animal-FreeIGF-I/IGF-1 protein, expressed by E. coli , with C-His labeled tag.

HY-P71415

	ULBP1/RAET1I Protein, Mouse (HEK293, His) ULBP1; RAET1I; NKG2DL1	Mouse	HEK293
	UL16 binding protein 1 (Ulbp1) is a membrane ligand of natural killer group 2, member D (NKG2D) which activates immune system on NK cells and T cells. Binding of Ulbp1 to NKG2D leads to activation of JAK2, STAT5, ERK and PI3K/Akt pathways, positive regulating immune response, interferon-gamma production and leukocyte activation. The effect of Ulbp1 can be inhibited by binding to UL16. ULBP1/RAET1I Protein, Mouse (HEK293, His) is the recombinant mouse-derived ULBP1/RAET1I protein, expressed by HEK293 , with C-6*His labeled tag. The total length of ULBP1/RAET1I Protein, Mouse (HEK293, His) is 186 a.a., with molecular weight of 30-40 kDa.

HY-P71618

	KRT35 Protein, Human (His-SUMO) Hair keratin; Hair keratin; type I Ha5; HHA5; HKA5; K35; Keratin; Keratin; type I cuticular Ha5; Keratin-35; KRT35; KRTHA5; type I cuticular Ha5; type I Ha5	Human	E. coli
	KRT35 Protein shows early expression in the hair follicle, primarily localized in supramatricial and lowermost cortical cells of the hair bulb. KRT35 Protein, Human (His-SUMO) is the recombinant human-derived KRT35 protein, expressed by E. coli , with N-His, N-SUMO labeled tag.

HY-P75503A

	Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, His) Apolipoprotein L1; Apo-L; ApoL-I; APOL1; APOL	Mouse	HEK293
	The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P7741

	Casein Kinase I gamma-2 Protein, Human (His) rHuCasein kinase I isoform gamma-2, His; Casein kinase I isoform gamma-2; CK1G2; CSNK1G2	Human	E. coli
	Casein kinase I gamma-2 Protein, Human (His) is an approximately 55.0 kDa human casein kinase I isoform gamma-2 protein with a His-flag expressed in E. coli. Human Casein kinase I isoform gamma-2 may exhibit overexpression during tumorigenesis and belongs to the CKI family.

HY-P701605

	EIF4A1 Protein, Human EIF4A1; Eukaryotic initiation factor 4A-I; eIF-4A-I; eIF4A-I; ATP-dependent RNA helicase eIF4A-1	Human	E. coli
	The EIF4A1 protein is an ATP-dependent RNA helicase and an important subunit of the eIF4F complex, which is essential for cap recognition and promoting the binding of mRNA to ribosomes. In the translation initiation model, EIF4A1 helps unravel RNA secondary structure in the mRNA 5'-UTR. EIF4A1 Protein, Human is the recombinant human-derived EIF4A1 protein, expressed by E. coli , with tag free. The total length of EIF4A1 Protein, Human is 406 a.a., .

HY-P78458

	IGF-I R Protein, Human (HEK293, His-Avi) CD221; IGF1R; IGF-1R; IGF-I R; IGF-I receptor; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216	Human	HEK293
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His-Avi) is the recombinant human-derived IGF-I R protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of IGF-I R Protein, Human (HEK293, His-Avi) is 902 a.a., with molecular weight of 110-130 kDa (alpha subunit) & 52-55 kDa (beta subunit), respectively.

HY-P75503

	Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, His, solution) Apolipoprotein L1; Apo-L; ApoL-I; APOL1; APOL	Mouse	HEK293
	The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, His, solution) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-His labeled tag.

HY-P702395

	Oleosin L Protein, Sesamum indicum (Cell-Free, His) Oleosin L; Allergen Ses i 5; Oleosin 15 kDa	Others	E. coli Cell-free
	The oleosin L protein plays a structural role in stabilizing liposomes during seed drying, preventing oil coalescence and affecting liposome integrity. Its potential interactions with lipid and phospholipid moieties suggest the involvement of multiple molecules. Oleosin L Protein, Sesamum indicum (Cell-Free, His) is the recombinant Oleosin L protein, expressed by E. coli Cell-free , with N-10*His labeled tag. The total length of Oleosin L Protein, Sesamum indicum (Cell-Free, His) is 145 a.a., with molecular weight of 16.7 kDa.

HY-P78142

	IGF-I R Protein, Human (Biotinylated, HEK293, His-Avi) CD221; IGF1R; IGF-1R; IGF-I R; IGF-I receptor; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216	Human	HEK293
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of IGF-I R Protein, Human (Biotinylated, HEK293, His-Avi) is 902 a.a., with molecular weight of 110-120 kDa (alpha subunit) & 52-55 kDa (beta subunit), respectively.

HY-P701606

	EIF4A1 Protein, Human (His, Strep) EIF4A1; Eukaryotic initiation factor 4A-I; eIF-4A-I; eIF4A-I; ATP-dependent RNA helicase eIF4A-1	Human	E. coli
	The EIF4A1 protein is an ATP-dependent RNA helicase and an important subunit of the eIF4F complex, which is essential for cap recognition and promoting the binding of mRNA to ribosomes. In the translation initiation model, EIF4A1 helps unravel RNA secondary structure in the mRNA 5'-UTR. EIF4A1 Protein, Human (His, Strep) is the recombinant human-derived EIF4A1 protein, expressed by E. coli , with N-Strep, N-6*His labeled tag. The total length of EIF4A1 Protein, Human (His, Strep) is 406 a.a., .

HY-P702822

	YBX1 Protein, Mouse (P.pastoris, His) Ybx1; Msy-1; Msy1; Nsep1; Yb1; Y-box-binding protein 1; YB-1; CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Nuclease-sensitive element-binding protein 1; Y-box transcription factor	Mouse	P. pastoris
	YBX1 Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived YBX1, expressed by P. pastoris , with N-6*His labeled tag. ,

HY-P71445

	CPS1/CPSase I Protein, Human (Sf9, His) Carbamoyl phosphate synthase; Carbamoyl phosphate synthase mitochondrial; Carbamoyl phosphate synthase; Carbamoyl phosphate synthetase 1; Carbamoyl phosphate synthetase 1 mitochondrial; Carbamoyl phosphate synthetase I; Carbamoyl-phosphate synthase [ammonia]; Carbamoyl-phosphate synthetase I; Carbamoylphosphate synthase; Carbamoylphosphate synthetase 1; Carbamoylphosphate synthetase I; CPS 1; Cps1; CPSase 1; CPSase I; CPSASE1; mitochondrial; MS738	Human	Sf9 insect cells
	The CPS1/CPSase I protein is critical in participating in the urea cycle and is essential for the elimination of excess ammonia in urea-bearing animals. This essential enzyme converts toxic ammonia (a byproduct of amino acid catabolism) into urea, promoting safe excretion. CPS1/CPSase I Protein, Human (Sf9, His) is the recombinant human-derived CPS1/CPSase I protein, expressed by Sf9 insect cells , with His labeled tag.

HY-P703163

	Menin Protein, Human (His, M327I) SCG2	Human	E. coli
	The Menin protein is an important component of the MLL/SET1 HMT complex, which methylates “Lys-4” of histone H3. It acts as a transcriptional regulator, inhibiting telomerase expression and inhibiting cell proliferation through TGFB1. Menin Protein, Human (His, M327I) is the recombinant human-derived Menin, expressed by E. coli , with His labeled tag. ,

HY-P71700

	HLA-C Protein, Human (His) HLA class I histocompatibility antigen, C alpha chain; HLA-C protein; MHC class I antigen; HLA-Cw	Human	E. coli
	HLA-C Protein, part of the MHC class I family, is crucial for immune system functions, presenting antigens to cytotoxic T cells. In this family, HLA-C is involved in regulating immune responses and recognizing foreign substances. Further exploration is needed to reveal specific functions and implications within the broader MHC class I family, emphasizing its significance in immune surveillance and host defense mechanisms. HLA-C Protein, Human (His) is the recombinant human-derived HLA-C protein, expressed by E. coli , with N-6*His labeled tag. The total length of HLA-C Protein, Human (His) is 284 a.a., with molecular weight of ~36.7 kDa.

HY-P72170

	DDX58 Protein, Human (His) Antiviral innate immune response receptor RIG-I; DEAD box protein 58; RLR-1; RIG-I	Human	E. coli
	The DDX58 protein is an innate immune receptor that detects cytoplasmic viral nucleic acids and initiates a signaling cascade for type I interferon production.It forms ribonucleoprotein complexes with viral RNA and promotes homo-oligomerization.DDX58 Protein, Human (His) is the recombinant human-derived DDX58 protein, expressed by E.coli , with N-6*His labeled tag.

HY-P72872

	Casein Kinase I alpha Protein, Human (sf9, GST) Casein kinase I isoform alpha; CKI-alpha; CK1; CSNK1A1	Human	Sf9 insect cells
	Casein kinase I α is a member of casein kinases that exhibits a preference for phosphorylation of acidic proteins such as casein. It phosphorylates many substrates, including CTNNB1 at "Ser-45" involved in Wnt signaling. Casein Kinase I alpha Protein, Human (sf9, GST) is the recombinant human-derived Casein Kinase I alpha protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of Casein Kinase I alpha Protein, Human (sf9, GST) is 337 a.a., with molecular weight of ~62 kDa.

HY-P77137

	PGLYRP4/PGRP-I beta Protein, Human (HEK293, His) Peptidoglycan recognition protein 4; PGRP-I-beta; PGRPIB; SBBI67	Human	HEK293
	PGLYRP4/PGRP-I beta protein is a model receptor that binds to the cell wall peptide peptidoglycan (PGN) in Gram-positive bacteria and exerts bactericidal activity by interfering with peptidoglycan biosynthesis. Its antimicrobial properties extend to Gram-negative bacteria, although it also binds to them. PGLYRP4/PGRP-I beta Protein, Human (HEK293, His) is the recombinant human-derived PGLYRP4/PGRP-I beta protein, expressed by HEK293 , with C-His labeled tag.

HY-P701788

	IKKε Protein, Human (Sf9, GST) IKKε; Inhibitor of nuclear factor kappa-B kinase subunit epsilon; I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IkBKE; Inducible I kappa-B kinase; IKK-i	Human	Sf9 insect cells
	IKKε protein is a serine/threonine kinase that coordinates the inflammatory response to viral infection by activating type I IFN, NF-kappa-B, and STAT signaling pathways. Upon activation of the viral RNA sensor, IKKε binds to DDX3X and phosphorylates IRF3, IRF7, and DDX3X, resulting in IRF3 nuclear translocation. IKKε Protein, Human (Sf9, GST) is the recombinant human-derived IKKε protein, expressed by Sf9 insect cells , with N-GST labeled tag. The total length of IKKε Protein, Human (Sf9, GST) is 715 a.a., .

HY-P71667

	HLA-G Protein, Human (HEK293, His) B2 microglobulin; DADB-15K14.8; HLA 6.0; HLA class I histocompatibility antigen alpha chain G; Major histocompatibility complex class I G; MHC class I antigen; MHC class I antigen G; MHC G; T-cell A locus; TCA	Human	HEK293
	HLA-G is a nonclassical major histocompatibility class Ib molecule that is critical for immune regulation at the maternal-fetal interface. It cooperates with B2M to form a complex that selectively binds self-peptides to promote maternal-fetal tolerance by interacting with KIR2DL4, LILRB1, and LILRB2 receptors. HLA-G Protein, Human (HEK293, His) is the recombinant human-derived HLA-G protein, expressed by HEK293 , with N-His labeled tag.

HY-P703192

	SET Protein, Human (His, Strep) Protein SET; HLA-DR-associated protein II; Inhibitor of granzyme A-activated DNase; IGAAD; PHAPII; Phosphatase 2A inhibitor I2PP2A; I-2PP2A; Template-activating factor I; TAF-I; SET; Homo sapiens; Human; IGAAD; Chaperone; DNA-binding	Human	E. coli
	SET Protein, Human (His, Strep) is the recombinant human-derived SET, expressed by E. coli , with Strep, His labeled tag. ,

HY-P73536

	Zika virus E/Envelope Protein (Domain I, His-MBP) Zika virus (ZIKV) (strain Zika SPH2015) E/Envelope protein (Domain I, His-MBP)	Virus	E. coli
	Genome polyprotein is a smaller protein chain of covalent linkages that is a key component of virus survival and replication. Zika virus E/Envelope Protein (Domain I, His-MBP) is the recombinant Virus-derived Zika virus E/Envelope protein, expressed by E. coli , with N-His, N-MBP labeled tag. Zika virus E/Envelope Protein (Domain I, His-MBP), has molecular weight of ~57.2 kDa.

HY-P72606

	IGF-I R Protein, Human (HEK293, His) Insulin-like growth factor 1 receptor; IGF-I receptor; IGF1R; CD221	Human	HEK293
	IGF-I receptor (IGF1R) mediates insulin-like growth factor effects, binding strongly to IGF1. Activation triggers PI3K-AKT/PKB and Ras-MAPK pathways, influencing cell survival, protein synthesis, and proliferation. IGF1R also signals through JAK/STAT, inhibiting JNK activation. Hybrid receptors show variable binding to IGF1 and insulin. IGF-I R Protein, Human (HEK293, His) is the recombinant human-derived IGF-I R protein, expressed by HEK293 , with C-6*His labeled tag. The total length of IGF-I R Protein, Human (HEK293, His) is 902 a.a., with molecular weight of 100-130 & 54 kDa, respectively.

HY-P72812

	Activin RIA Protein, Human (HEK293, His-Fc) Activin receptor type-1; ACTR-I; ALK-2; SKR1; TSR-I; ACVR1; ACVRLK2	Human	HEK293
	Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. Activin RIA Protein, Human (HEK293, His-Fc) is produced in HEK293 cells with a C-Terminal His-tag and a C-Terminal Fc-tag . It consists of 124 amino acids (M1-V124).

HY-P75538

	ACVR1 Protein, Rat (HEK293, hFc) Activin receptor type-1; ACTR-I; SKR1; TSR-I; TSK-7L; Acvrlk2; Tgfb1	Rat	HEK293
	Activin A receptor, type I (ACVR1), also known as ALK-2, is a bone morphogenetic protein (BMP) type I receptor. ACVR1 is involved in a wide variety of biological processes, including bone, heart, cartilage, nervous, and reproductive system development and regulation. ACVR1 Protein, Rat (HEK293, hFc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of 103 amino acids (M21-E123).

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HY-P80702

	Hexokinase I Antibody (YA739) HK1; Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I	WB	Human, Mouse, Rat
	Hexokinase I Antibody (YA739) is a non-conjugated and Mouse origined monoclonal antibody about 102 kDa, targeting to Hexokinase I (6B8). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80382

	Carbonic Anhydrase I Antibody	WB, IHC-P	Human, Mouse, Rat
	Carbonic Anhydrase I is a non-conjugated and Rabbit origined monoclonal antibody about 29 kDa, targeting to Carbonic Anhydrase I . It can be used for WB,IHC-P assays with tag free, in the background of Human, Mouse, Rat.

HY-P80627

	Collagen I alpha 2 Antibody Collagen alpha-2(I) chain (Alpha-2 type I collagen)	WB, IHC-F, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	Collagen I alpha 2 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 129 kDa, targeting to Collagen I alpha 2. It can be used for WB,IHC-F,IHC-P,ICC/IF,ELISA assays with tag free, in the background of Human, Mouse, Rat.

HY-P81227

	Collagen I Antibody Collagen type I; Alpha 1 type I collagen; Alpha 2 type I collagen; COL1A1; COL1A2; Collagen I alpha 1 polypeptide; Collagen I alpha 2 polypeptide; Collagen Of Skin Tendon And Bone; Collagen Type 1; Collagen type I alpha 1; Collagen type I alpha 2; OI4; Osteogenesis Imperfecta Type IV; Pro alpha 1(I) collagen; Type I procollagen; CO1A1_HUMAN.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat, Rabbit
	Collagen I Antibody is an unconjugated, approximately 130 kDa, rabbit-derived, anti-Collagen I polyclonal antibody. Collagen I Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, rat, rabbit, and predicted: chicken, dog, cow, sheep background without labeling.

HY-P83577

	MHC Class I Antibody (YA3322) Aw-68; HLA class I histocompatibility antigen; A-28 alpha chain; MHC class I antigen A*68; HLA-A; MHC class I antigen HLA A heavy chain	WB, IHC-P	Human
	MHC Class I Antibody (YA3322) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3322), targeting MHC Class I, with a predicted molecular weight of 41 kDa (observed band size: 41 kDa). MHC Class I Antibody (YA3322) can be used for WB, IHC-P experiment in human background.

HY-P82492

	Topoisomerase I Antibody (YA2237) TOP1; DNA topoisomerase 1; DNA topoisomerase I	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	Topoisomerase I Antibody (YA2237) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2237), targeting Topoisomerase I, with a predicted molecular weight of 91 kDa (observed band size: 91 kDa). Topoisomerase I Antibody (YA2237) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human, mouse, rat background.

HY-P81440

	HMGA1 Antibody (YA1185) HMG R; HMG-I(Y); HMGA1; HMGA1A; HMGIY	IHC-P	Human
	HMGA1 Antibody (YA1185) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1185), targeting HMGA1. HMGA1 Antibody (YA1185) can be used for IHC-P experiment in human background.

HY-P82087

	Troponin I Antibody (YA1832) TNNI2; Troponin I; fast skeletal muscle; Troponin I; fast-twitch isoform	WB, IP	Human, Mouse, Rat
	Troponin I Antibody (YA1832) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1832), targeting Troponin I, with a predicted molecular weight of 21 kDa (observed band size: 21 kDa). Troponin I Antibody (YA1832) can be used for WB, IP experiment in human, mouse, rat background.

HY-P81144

	Cardiac Troponin I/TNNC1 Antibody troponin I type 3 (cardiac); Cardiac troponin I; Troponin I, cardiac muscle; Cardiomyopathy, familial hypertrophic, 7, included; CMD1FF; CMD2A; CMH7; cTnI; Familial hypertrophic cardiomyopathy 7; MGC116817; RCM1; Tn1; Tni; TNN I3; TNNC 1; TNNC-1; TNNC1; TNNI3; Troponin I cardiac; Troponin I cardiac muscle; Troponin I cardiac muscle isoform; Troponin I type 3 cardiac; troponin I, cardiac 3; TroponinI; Troponin I; TNNI3_HUMAN.	WB, IHC-P, ICC/IF, IP	Human
	Cardiac Troponin I/TNNC1 Antibody is an unconjugated, approximately 23 kDa, rabbit-derived, anti-Cardiac Troponin I/TNNC1 monoclonal antibody. Cardiac Troponin I/TNNC1 Antibody can be used for:WB,IHC-P,ICC/IF,IP expriments in human background without labeling.

HY-P81062

	Sudan I Antibody (YA905) SudanI	ELISA
	Sudan I Antibody (YA905) is an unconjugated, rabbit-derived, anti-Sudan I (YA905) monoclonal antibody. Sudan I Antibody (YA905) can be used for: ELISA expriments in background without labeling.

HY-P82237

	Carbonic Anhydrase 1 Antibody (YA1982) CA1; Carbonic anhydrase 1; Carbonate dehydratase I; Carbonic anhydrase B; CAB; Carbonic anhydrase I; CA-I	WB, IHC-P, ICC/IF	Human, Mouse, Rat, Zebrafish
	Carbonic Anhydrase 1 Antibody (YA1982) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1982), targeting Carbonic Anhydrase 1, with a predicted molecular weight of 29 kDa (observed band size: 29 kDa). Carbonic Anhydrase 1 Antibody (YA1982) can be used for WB, IHC-P, ICC/IF experiment in human, mouse, rat, zebra fish background.

HY-P83523

	General Transcription Factor II I Antibody (YA3268) GTF2I; BAP135; WBSCR6; General transcription factor II-I; GTFII-I; TFII-I; Bruton tyrosine kinase-associated protein 135; BAP-135; BTK-associated protein 135; SRF-Phox1-interacting protein; SPIN; Williams-Beuren syndrome chromosomal region	WB, IHC-F, IHC-P, ICC/IF	Human
	General Transcription Factor II I Antibody (YA3268) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3268), targeting General Transcription Factor II I, with a predicted molecular weight of 112 kDa (observed band size: 135/138 kDa). General Transcription Factor II I Antibody (YA3268) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human background.

HY-P80936

	YB1 Antibody YBX1; NSEP1; YB1; Nuclease-sensitive element-binding protein 1; CCAAT-binding transcription factor I subunit A; CBF-A; DNA-binding protein B; DBPB; Enhancer factor I subunit A; EFI-A; Y-box transcription factor; Y-box-binding protein 1; YB-	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	YB1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 36 kDa, targeting to YB1. It can be used for WB,IHC-P,ICC/IF,IP,FC assays with tag free, in the background of Human, Mouse, Rat.

HY-P82119

	Phospho-Synapsin I (Ser9) Antibody (YA1864) SYN1; Synapsin-1; Brain protein 4.1; Synapsin I	WB, IHC-P	Human, Rat
	Phospho-Synapsin I (Ser9) Antibody (YA1864) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1864), targeting Phospho-Synapsin I (Ser9), with a predicted molecular weight of 74 kDa (observed band size: 77 kDa). Phospho-Synapsin I (Ser9) Antibody (YA1864) can be used for WB, IHC-P experiment in human, rat background.

HY-P80650

	eIF4A1 Antibody (YA774) Eukaryotic initiation factor 4A-I; eIF-4A-I; eIF4A-I; ATP-dependent RNA helicase eIF4A-1	WB, IHC-F, IHC-P, ICC/IF	Human, Mouse, Rat
	eIF4A1 Antibody (YA774) is a non-conjugated and Mouse origined monoclonal antibody about 46 kDa, targeting to eIF4A1 (6D7). It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human, Mouse, Rat.

HY-P81137

	APOA1 Antibody Apo-AI; ApoA I; ApoA-I; APOA1_HUMAN; Apolipoprotein A-I(1-242); Apolipoprotein A1; Apolipoprotein A 1; Apolipoprotein AI; Apolipoprotein A I; Brp14; Ltw1; Lvtw1; Sep1; Sep2.	WB, IHC-P, ICC/IF, IP	Human, Mouse
	APOA1 Antibody is an unconjugated, approximately 31 kDa, rabbit-derived, anti-APOA1 monoclonal antibody. APOA1 Antibody can be used for: WB,IHC-P,ICC/IF,IP expriments in human, mouse background without labeling.

HY-P81183

	Cytokeratin 19 Antibody 40 kDa keratin intermediate filament; CK 19; ck19; CK19; CK-19; KRT19; Cytokeratin19; Cytokeratin-19; k19; k1cs; Keratin 19; Keratin-19; Keratin type I 40 kD; Keratin type i 40kD; Keratin type I cytoskeletal 19; krt19; mgc15366; K1C19_HUMAN; Keratin, type I cytoskeletal 19; Keratin, type I, 40 kd.	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse
	Cytokeratin 19 Antibody is an unconjugated, approximately 44 kDa, rabbit-derived, anti-Cytokeratin 19 polyclonal antibody. Cytokeratin 19 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, and predicted: rat, chicken, dog, pig, cow, horse, rabbit background without labeling.

HY-P81891

	MGST1 Antibody (YA1636) Microsomal GST-I	WB, IHC-P	Human, Rat
	MGST1 Antibody (YA1636) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1636), targeting MGST1, with a predicted molecular weight of 18 kDa (observed band size: 18 kDa). MGST1 Antibody (YA1636) can be used for WB, IHC-P experiment in human, rat background.

HY-P82751

	Chromogranin A Antibody (YA2496) beta Granin; Chromogranin A; ChrA; SP-I; Vasostatin I; Vasostatin-2; Vasostatin II; Pancreastatin; CHGA	WB	Rat
	Chromogranin A Antibody (YA2496) is a biotin-conjugated non-conjugated IgG antibody, targeting Chromogranin A, with a predicted molecular weight of 51 kDa (observed band size: 92 kDa). Chromogranin A Antibody (YA2496) can be used for WB experiment in rat background.

HY-P83195

	HLA A Antibody (YA2940) Aw-68; HLA class I histocompatibility antigen; A-28 alpha chain; MHC class I antigen A*68; HLA-A; MHC class I antigen HLA A heavy chain	WB, IHC-P, ICC/IF, IP, FC	Human
	HLA A Antibody (YA2940) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2940), targeting HLA A, with a predicted molecular weight of 41 kDa (observed band size: 41 kDa). HLA A Antibody (YA2940) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human background.

HY-P83556

	SUMO Conjugating Enzyme UBC9 Antibody (YA3301) UBE2I; UBC9; UBCE9; SUMO-conjugating enzyme UBC9; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; Ubiquitin-conjugating enzyme E2 I; Ubiquitin-protein ligase I; p18	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	SUMO Conjugating Enzyme UBC9 Antibody (YA3301) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3301), targeting SUMO Conjugating Enzyme UBC9, with a predicted molecular weight of 18 kDa (observed band size: 18 kDa). SUMO Conjugating Enzyme UBC9 Antibody (YA3301) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

HY-P81250

	Cytokeratin 19 Antibody (YA924) 40 kDa keratin intermediate filament; CK 19; ck19; CK19; CK-19; KRT19; Cytokeratin19; Cytokeratin-19; k19; k1cs; Keratin 19; Keratin-19; Keratin type I 40 kD; Keratin type i 40kD; Keratin type I cytoskeletal 19; krt19; mgc15366; K1C19_HUMAN; Keratin, type I cytoskeletal 19; Keratin, type I, 40 kd	WB, IHC-P, ICC/IF, IP	Human, Rat
	Cytokeratin 19 Antibody is an unconjugated, approximately 44 kDa, rabbit-derived, anti-Cytokeratin 19 monoclonal antibody. Cytokeratin 19 Antibody can be used for: WB,IHC-F,IHC-P,ICC/IF,IP expriments in human, rat background without labeling.

HY-P81183A

	Cytokeratin 19 Antibody(PBS only) 40 kDa keratin intermediate filament; CK 19; ck19; CK19; CK-19; KRT19; Cytokeratin19; Cytokeratin-19; k19; k1cs; Keratin 19; Keratin-19; Keratin type I 40 kD; Keratin type i 40kD; Keratin type I cytoskeletal 19; krt19; mgc15366; K1C19_HUMAN; Keratin, type I cytoskeletal 19; Keratin, type I, 40 kd.	WB, IHC-P, IHC-F, ICC/IF, FC, ELISA	Human, Mouse
	Cytokeratin 19 Antibody is an unconjugated, approximately 44 kDa, rabbit-derived, anti-Cytokeratin 19 polyclonal antibody. Cytokeratin 19 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, mouse, and predicted: rat, chicken, dog, pig, cow, horse, rabbit background without labeling.

HY-P82148

	ApoL1 Antibody (YA1893) APOL1; APOL; Apolipoprotein L1; Apolipoprotein L; Apo-L; ApoL; Apolipoprotein L-I; ApoL-I	WB, ICC/IF, IP, FC	Human
	ApoL1 Antibody (YA1893) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1893), targeting ApoL1, with a predicted molecular weight of 44 kDa (observed band size: 44 kDa). ApoL1 Antibody (YA1893) can be used for WB, ICC/IF, IP, FC experiment in human background.

HY-P80745

	Liver Arginase Antibody Liver-type arginase; Type I arginase	WB, IHC-P	Mouse, Rat
	Liver Arginase Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 35 kDa, targeting to Liver Arginase. It can be used for WB,IHC-P assays with tag free, in the background of Mouse, Rat.

HY-P81974

	Prealbumin Antibody (YA1719) Prealbumin; TBPA; Amyloidosis I; Transthyretin	WB	Rat
	Prealbumin Antibody (YA1719) is a biotin-conjugated non-conjugated IgG antibody, targeting Prealbumin, with a predicted molecular weight of 16 kDa (observed band size: 16 kDa). Prealbumin Antibody (YA1719) can be used for WB experiment in rat background.

HY-P82045

	DNA Ligase I Antibody (YA1790) LIG1; DNA ligase 1; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1	WB, IHC-P, ICC/IF	Human, Rat
	DNA Ligase I Antibody (YA1790) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1790), targeting DNA Ligase I, with a predicted molecular weight of 102 kDa (observed band size: 140 kDa). DNA Ligase I Antibody (YA1790) can be used for WB, IHC-P, ICC/IF experiment in human, rat background.

HY-P83364

	PPP1R1A Antibody (YA3109) I 1; I1; Inhibitor 1; IPP1; Ppp1r1a; Protein phosphatase 1 regulatory (inhibitor) subunit 1A	WB, IHC-P, ICC/IF, IP, FC	Human, Mouse, Rat
	PPP1R1A Antibody (YA3109) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3109), targeting PPP1R1A, with a predicted molecular weight of 19 kDa (observed band size: 27 kDa). PPP1R1A Antibody (YA3109) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.

HY-P81743

	p150 CAF1 Antibody (YA1488) CHAF1A; CAF; CAF1P150; Chromatin assembly factor 1 subunit A; CAF-1 subunit A; Chromatin assembly factor I p150 subunit; CAF-I 150 kDa subunit; CAF-I p150; hp150	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	p150 CAF1 Antibody (YA1488) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1488), targeting p150 CAF1, with a predicted molecular weight of 107 kDa (observed band size: 150 kDa). p150 CAF1 Antibody (YA1488) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human background.

HY-P82190

	SET Antibody (YA1935) 2PP2A; IGAAD; TAF-I; I2PP2A; IPP2A2; PHAPII; TAF-IBETA	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	SET Antibody (YA1935) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1935), targeting SET, with a predicted molecular weight of 33 kDa (observed band size: 39 kDa). SET Antibody (YA1935) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human background.

HY-P81480

	IL-4I1/LAO Antibody (YA1225) IL4I1; FIG1 ; UNQ636/PRO1265 ; L-amino-acid oxidase ; Interleukin-4-induced protein 1; hIL4I1 ; Protein Fig-1 ; LAAO; LAO	IHC-P	Human
	IL-4I1/LAO Antibody (YA1225) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1225), targeting IL-4I1/LAO. IL-4I1/LAO Antibody (YA1225) can be used for IHC-P experiment in human background.

HY-P81866

	IKK epsilon Antibody (YA1611) IKBKE; IKKE; IKKI; KIAA0151; Inhibitor of nuclear factor kappa-B kinase subunit epsilon; I-kappa-B kinase epsilon; IKK-E; IKK-epsilon; IkBKE; Inducible I kappa-B kinase; IKK-i	WB, IHC-P, ICC/IF, FC	Human
	IKK epsilon Antibody (YA1611) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1611), targeting IKK epsilon, with a predicted molecular weight of 80 kDa (observed band size: 80 kDa). IKK epsilon Antibody (YA1611) can be used for WB, IHC-P, ICC/IF, FC experiment in human background.

HY-P80942

	GLO1 Antibody Aldoketomutase; glo1; GLOD1; Glx I; GLYI	WB, FC	Human, Mouse, Rat
	GLO1 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 21 kDa, targeting to Lactoylglutathione lyase (GLO1). It can be used for WB,FC assays in the background of Human, Mouse, Rat.

HY-P82107

	Rel B Antibody (YA1852) RELB; Transcription factor RelB; I-Rel	WB, IP	Human, Mouse, Rat
	Rel B Antibody (YA1852) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1852), targeting Rel B, with a predicted molecular weight of 62 kDa (observed band size: 62 kDa). Rel B Antibody (YA1852) can be used for WB, IP experiment in human, mouse, rat background.

HY-P82002

	Proteasome beta 9 Antibody (YA1747) Beta1i; LMP2; PSMB 9; PSMB6i; PSMB9; RING12	WB, ICC/IF	Human, Mouse, Rat
	Proteasome beta 9 Antibody (YA1747) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1747), targeting Proteasome beta 9, with a predicted molecular weight of 23 kDa (observed band size: 23 kDa). Proteasome beta 9 Antibody (YA1747) can be used for WB, ICC/IF experiment in human, mouse, rat background.

HY-P80717

	IGF1 Receptor Antibody IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221	WB, IHC-P	Human
	IGF1 Receptor Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 155 kDa, targeting to IGF1 Receptor. It can be used for WB,IHC-P assays with tag free, in the background of Human.

HY-P83390

	P2Y12 Antibody (YA3135) HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc)	WB, IP	Human
	P2Y12 Antibody (YA3135) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3135), targeting P2Y12, with a predicted molecular weight of 39 kDa (observed band size: 52 kDa). P2Y12 Antibody (YA3135) can be used for WB, IP experiment in human background.

HY-P83701

	HLA E Antibody (YA3437) HLA class I histocompatibility antigen E alpha chain antibody; EA1.2 antibody; EA2.1 antibody; HLA 6.2 antibody; HLA class I histocompatibility antigen alpha chain E antibody; HLA class I histocompatibility antigen E alpha chain precursor antibody; HLA class I histocompatibility antigen E alpha chain precursor antibody; HLA6.2 antibody; HLAE antibody; Lymphocyte antigen antibody; Major histocompatibility complex class I E antibody; MHC antibody; MHC class I antigen E antibody; MHC HLA E alpha 1 antibody; MHC HLA E alpha 2.1 antibody; QA1 antibody	WB, IP, FC	Human
	HLA E Antibody is a non-conjugated and Mouse origined monoclonal antibody about 40 kDa, targeting to HLA E . It can be used for WB, IP, FC assays with tag free, in the background of Human.

HY-P82022

	PSMB10 Antibody (YA1767) LMP10; MECL1; beta2i	WB	Human, Rat
	PSMB10 Antibody (YA1767) is a biotin-conjugated non-conjugated IgG antibody, targeting PSMB10, with a predicted molecular weight of 29 kDa (observed band size: 29 kDa). PSMB10 Antibody (YA1767) can be used for WB experiment in human, rat background.

HY-P80876

	Proteasome beta 8 Antibody (YA684) PSMB8; LMP7; PSMB5i; RING10; Y2; Proteasome subunit beta type-8; Low molecular mass protein 7; Macropain subunit C13; Multicatalytic endopeptidase complex subunit C13; Proteasome component C13; Proteasome subunit beta-5i; Really interesting	WB, IHC-F, IHC-P, ICC/IF	Human, Rat
	Proteasome beta 8 Antibody (YA684) is a non-conjugated and Mouse origined monoclonal antibody about 30 kDa, targeting to Proteasome beta 8 (3G3). It can be used for WB,IHC-F,IHC-P,ICC/IF assays with tag free, in the background of Human, Rat.

HY-P81207

	TNMD Antibody BRICD4; BRICHOS domain containing 4; CHM1 LIKE; CHM1L; Chondromodulin I like; Chondromodulin I like protein; Chondromodulin-1-like protein; Chondromodulin-I-like protein; hChM1L; hTeM; Myodulin; TEM; Tendin; Tenomodulin; Tenomodulin protein; TNMD; TNMD_HUMAN; UNQ771/PRO1565.	WB, ELISA, IHC-P, IHC-F, ICC/IF	Human, Mouse, Rat
	TNMD Antibody is an unconjugated, approximately 37 kDa, rabbit-derived, anti-TNMD polyclonal antibody. TNMD Antibody can be used for: WB, ELISA, IHC-P, IHC-F, IF expriments in human, mouse, rat, and predicted: dog, pig, cow, horse, rabbit, sheep background without labeling.

HY-P80758

	MSR1 Antibody Macrophage scavenger receptor types I and II; Macrophage acetylated LDL receptor I and II; Scavenger receptor class A member 1; CD204; MSR1; SCARA1	WB	Human, Mouse, Rat
	MSR1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 50 kDa, targeting to MSR1. It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80825

	Phospho-IGF1 Receptor (Tyr1166) Antibody IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221	WB, IP	Human, Mouse, Rat
	Phospho-IGF1 Receptor (Tyr1166) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 155 kDa, targeting to Phospho-IGF1 Receptor (Tyr1166). It can be used for WB,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P82573

	DDX58 Antibody (YA2318) RIG-I-like receptor 1; RLR-1; RLR1; Retinoic acid-inducible gene 1 protein; RIG-1; RIG1; RIG-I; RIGI	WB, IP	Human
	DDX58 Antibody (YA2318) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2318), targeting DDX58, with a predicted molecular weight of 107 kDa (observed band size: 107 kDa). DDX58 Antibody (YA2318) can be used for WB, IP experiment in human background.

HY-P82401

	ARFGEF2 Antibody (YA2146) BIG2; PVNH2; dJ1164I10.1	WB	Human, Mouse, Rat
	ARFGEF2 Antibody (YA2146) is a biotin-conjugated non-conjugated IgG antibody, targeting ARFGEF2, with a predicted molecular weight of 202 kDa (observed band size: 202 kDa). ARFGEF2 Antibody (YA2146) can be used for WB experiment in human, mouse, rat background.

HY-P81946

	P2Y6 Antibody (YA1691) P2ry6; P2Y6; P2Y6 receptor; PP2891	WB, IHC-F, IHC-P, ICC/IF, IP	Human
	P2Y6 Antibody (YA1691) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1691), targeting P2Y6, with a predicted molecular weight of 36 kDa (observed band size: 36 kDa). P2Y6 Antibody (YA1691) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human background.

HY-P82051

	Profilin 1 Antibody (YA1796) Epididymis tissue protein Li 184a; Profilin I	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	Profilin 1 Antibody (YA1796) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1796), targeting Profilin 1, with a predicted molecular weight of 15 kDa (observed band size: 15 kDa). Profilin 1 Antibody (YA1796) can be used for WB, IHC-F, IHC-P, ICC/IF, IP experiment in human, mouse, rat background.

HY-P82634

	Desmoplakin Antibody (YA2379) Desmoplakin I; Desmoplakin II; DPI; DPII; DSP; KPPS2; PPKS2	WB, ICC/IF, FC	Human, Rat
	Desmoplakin Antibody (YA2379) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2379), targeting Desmoplakin, with a predicted molecular weight of 332 kDa (observed band size: 270 kDa). Desmoplakin Antibody (YA2379) can be used for WB, ICC/IF, FC experiment in human, rat background.

HY-P83236

	CETP Antibody (YA2981) BPIFF; HDLCQ10; CETP; Lipid transfer protein I; Cholesteryl ester transfer protein	WB, IP	Human
	CETP Antibody (YA2981) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2981), targeting CETP, with a predicted molecular weight of 55 kDa (observed band size: 55 kDa). CETP Antibody (YA2981) can be used for WB, IP experiment in human background.

HY-P80544

	Annexin A1 Antibody (YA832) ANXA1; ANX1; LPC1; Annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 inhibitory protein; p35	WB	Human, Mouse, Rat, Monkey
	Annexin A1 Antibody (YA832) is a non-conjugated and Mouse origined monoclonal antibody about 39 kDa, targeting to Annexin A1 (5E4D8). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat, Monkey.

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Cat. No.	Product Name		Classification

HY-50713

Calcium-Sensing Receptor Antagonists I		Alkynes
Calcium-Sensing Receptor Antagonists I is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-146653

Glyoxalase I inhibitor 1		Alkynes
Glyoxalase I inhibitor 1 (compound 23) is a potent glyoxalase I (GLO1) inhibitor with an IC₅₀ of 26 nM . Glyoxalase I inhibitor 1 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-123420

Dinordrin Dinordrin I		Alkynes
Dinordrin (Dinordrin I) is a steroid with a luteolytic effect. Dinordrin can cause depression of both plasma estrogen and progesterone levels .

HY-107681

SIB-1508Y		Alkynes
SIB-1508Y is an orally active and selective nAChR agonist. SIB-1508Y has the potential to study parkinsonism . SIB-1508Y is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152478

3’-β-C-Ethynylguanosine		Alkynes
3’-β-C-Ethynylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) . 3’-β-C-Ethynylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154361

TLR7 agonist 13		Alkynes
TLR7 agonist 13 is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) . TLR7 agonist 13 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-154349

N2-iso-Butyroyl-2’-O-propargylguanosine		Alkynes
N2-iso-Butyroyl-2’-O-propargylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) . N2-iso-Butyroyl-2’-O-propargylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-152684

2′-O-2-Propyn-1-ylguanosine		Alkynes
2′-O-2-Propyn-1-ylguanosine is a guanosine analogue. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7) . 2′-O-2-Propyn-1-ylguanosine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-159450

PROTAC SMARCA2 degrader-6		Azide
PROTAC SMARCA2 degrader-6 (compound I-427) is a PROTAC degrader targeting SMARCA2; it degrades SMARCA2 proteins in A549 cells with an DC₅₀ <100 nM, and a maximum degradation rate (Dmax%) >90 after 24 h of treatment .

HY-159462

PROTAC SMARCA2 degrader-10		Azide
PROTAC SMARCA2 degrader-10 (compound I-507) is a PROTAC degrader targeting SMARCA2; it degrades SMARCA2 proteins in A549 cells with an DC₅₀ <100 nM, and a maximum degradation rate (Dmax%) >90 after 24 h of treatment .

HY-116925

L-767679		Alkynes
L-767679 (compound I) is a hydrophilic zwitterion with a low intestinal metabolism .

HY-159454

PROTAC SMARCA2/4-degrader-3		Azide
SMARCA2/4-degrader-3 (compound I-433) is a PROTAC SMARCA2/4-degrader based on VH032-NH2, with a degradation potency (DC₅₀) <100 nM in MV4-11 cells .

HY-159458

PROTAC SMARCA2/4-degrader-7		Azide
SMARCA2/4-degrader-7 (compound I-439) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4 proteins in A549 cells with the DC₅₀s <100 nM, and the maximum degradation rate (Dmax%) >90 after 24 h of treatment .

HY-159459

PROTAC SMARCA2/4-degrader-32		Azide
PROTAC SMARCA2/4-degrader-32 (compound I-446) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4 proteins in A549 cells with the DC₅₀s <100 nM, and the maximum degradation rate (Dmax%) >90 after 24 h of treatment .

HY-159452

PROTAC SMARCA2/4-degrader-1		Azide
SMARCA2/4-degrader-1 (compound I-430) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4 proteins in A549 cells with the DC₅₀s <100 nM, and the maximum degradation rate (Dmax%) >90 after 24 h of treatment .

HY-159453

PROTAC SMARCA2/4-degrader-2		Azide
SMARCA2/4-degrader-2 (compound I-431) is a PROTAC degrader targeting SMARCA2 and SMARCA4; it degrades SMARCA2/4 proteins in A549 cells with the DC₅₀s <100 nM, and the maximum degradation rate (Dmax%) >90 after 24 h of treatment .

HY-159457

PROTAC SMARCA2/4-degrader-6		Azide
PROTAC SMARCA2/4-degrader-6 (compound I-438) is a SMARCA2/4 degrader. PROTAC SMARCA2/4-degrader-6 has the potential for the research of cancer. (Blue:SMARCA2/4 ligand, (HY-159545); Black: linker (HY-W006635); Pink:VHL ligand (HY-112078)) .

HY-118197

L-669083		Azide
L-669083 is a leukotriene biosynthesis inhibitor whose structure is based on a mixture of indole and quinoline. In this study, a potent radioiodinated photoaffinity analog of L-689,037, [125I] L-691,678, was developed and characterized for immunoprecipitation studies showing that the quindole series of leukotriene biosynthesis inhibitors directly interact with FLAP. In addition, the results showed that MK-886, L-674,573, and L-689,037 competed with [125I] L-691,678 and [125I] L-669083 for binding to FLAP in a concentration-dependent manner, indicating that these three leukotriene biosynthesis inhibitors share a binding site on FLAP, further demonstrating that FLAP is a suitable target for structurally diverse leukotriene biosynthesis inhibitors.

HY-159112

AW01178		Azide
AW01178 is a Class I HDAC inhibitor. AW01178 induces the upregulation of E-cadherin at both mRNA and protein levels and inhibits the EMT of breast cancer cells .

HY-151742

Norbornene-methyl-NHS		TCO
Norbornene-methyl-NHS is a click chemistry reagent containing a TCO group. Dienophile for conjugation via Diels-Alder-reaction, i.e. copper-free click reaction with tetrazines .

HY-159449

PROTAC SMARCA2 degrader-5		Azide
PROTAC SMARCA2 degrader-5 (Compound I-425) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2. PROTAC SMARCA2 degrader-5 degrades SMARCA2 in MV411 and in A549 with DC₅₀ <100 nM, degrades SMARCA4 with DC₅₀ of 100-500 nM . (Pink: Ligand for target protein (HY-159531); Black: Linker (HY-159538); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845))

HY-159451

PROTAC SMARCA2 degrader-7		Azide
PROTAC SMARCA2 degrader-7 (Compound I-428) is a PROTAC degrader for SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A (SMARCA) SMARCA2. PROTAC SMARCA2 degrader-7 degrades SMARCA2 and SMARCA4 in MV411 with DC₅₀ of <100 and 100-500 nM. (Pink: Ligand for target protein (HY-159542); Black: Linker (HY-159538); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845))

HY-148908

TNF-α-IN-8		Azide
TNF-α-IN-8 (compound I-42) is a TNF-α inhibitor. TNF-α-IN-8 is an isoindole-imide compound. TNF-α-IN-8 can be used for the research of cancer, heart disease, osteoporosis, inflammatory, allergic and autoimmune diseases . TNF-α-IN-8 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-159461

PROTAC SMARCA2/4-degrader-9		Azide
PROTAC SMARCA2/4-degrader-9 (Compound I-503) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2 degrader-9 degrades SMARCA2 in MV411 and in A549 with DC₅₀ <100 nM, degrades SMARCA4 in MV411 with DC₅₀ <100 nM . (Pink: Ligand for target protein (HY-159545); Black: Linker (HY-W006635); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845))

HY-159460

PROTAC SMARCA2/4-degrader-8		Azide
PROTAC SMARCA2/4-degrader-8 (Compound I-502) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2. PROTAC SMARCA2/4-degrader-8 degrades SMARCA2 with DC₅₀ <100 nM in A549 and in MV411, degrades SMARCA4 with DC₅₀<100 nM in MV411(Pink: Ligand for target protein (HY-159545); Black: Linker (HY-W063924); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845))

HY-159455

PROTAC SMARCA2/4-degrader-4		Azide
PROTAC SMARCA2/4-degrader-4 (Compound I-434) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2/4-degrader-4 degrades SMARCA2 in MV411 and in A549 with DC₅₀ <100 nM, degrades SMARCA4 in MV411 with DC₅₀ <100 nM. (Pink: Ligand for target protein (HY-159472); Black: Linker (HY-159478); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845))

HY-159456

PROTAC SMARCA2/4-degrader-5		Azide
PROTAC SMARCA2/4-degrader-5 (Compound I-437) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2/4-degrader-5 degrades SMARCA2 in MV411 and in A549 with DC₅₀ <100 nM, degrades SMARCA4 in MV411 with DC₅₀ of 100-500 nM. (Pink: Ligand for target protein (HY-159545); Black: Linker (HY-159557); Blue: Ligand for E3 ligase (S,R,S)-AHPC (HY-125845))

HY-159128

hCAIX-IN-21		Azide
hCAIX-IN-21 (compound 16c) is a potent hCAIX inhibitor with K_I values of 5.2, 3.5, 12.6, 13600 nM for hCAIX, hCA II, hCA XII, hCA I, respectively. hCAIX-IN-21 inhibits cathepsin B enzyme activity .

HY-100495

FT011 1 Publications Verification		Alkynes
FT011 is an anti-fibrotic agent, reduces mRNA expression of collagens I and III and inhibits collagen synthesis . FT011 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W879007

ICG-azide		Azide
ICG-azide, a near infrared (NIR) fluorescent dye, is a copper (I)-catalyzed azide-alkyne cycloaddition (CuAAC) reagent. ICG-azide can be readily incorporated into dye-stabilized nanoemulsions and facilitate the attachment of targeting ligands via click-chemistry in a simple, scalable, and reproducible reaction .

HY-163964

Lenalidomide-C3-PEG3-N3		Azide
Lenalidomide-C3-PEG3-N3 is an E3 Ligase Ligand-Linker Conjugate. Lenalidomide-C3-PEG3-N3 can be used to synthesize L18I (HY-163962) .

HY-16200

Ethynylcytidine ECyD; TAS-106; 3'-C-Ethynylcytidine		Alkynes
Ethynylcytidine (ECyD), a nucleoside analog and a potent inhibitor of RNA synthesis, inhibits RNA polymerases I, II and II. Ethynylcytidine has robust antitumor activity in a wide range of models of cancer . Ethynylcytidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151730

(Me)Tz-butanoic acid		Tetrazine
(Me)Tz-butanoic acid is a click chemistry reagent containing an azide. (Me)Tz-butanoic acid is tetrazine linker for conjugation via Diels-Alder-reaction, i.e. copper-free Click reaction with dienophiles . (Me)Tz-butanoic acid is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-134723

DBCO-PEG4-GGFG-Dxd		DBCO
DBCO-PEG4-GGFG-Dxd is a agent-linker conjugate for ADC with potent antitumor activity by using Dxd (a DNA topoisomerase I inhibitor), linked via the cleavable ADC linker DBCO-PEG4-GGFG . DBCO-PEG4-GGFG-Dxd is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-146691

hMAO-B-IN-2		Alkynes
hMAO-B-IN-2 (compound 6j) is an orally active, potent, selective and BBB penetrated and competitive reversible hMAO-B inhibitor, with an IC₅₀ of 4 nM. hMAO-B-IN-2 shows low toxicity and good neuroprotective effects in SH-SY5Y cell. hMAO-B-IN-2 can be used for alzheimer’s disease research . hMAO-B-IN-2 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W040124

DL-Propargylglycine		Alkynes
DL-Propargylglycine is a Glycine (HY-Y0966) derivative . DL-Propargylglycine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151687

Fmoc-L-Tyr(2-azidoethyl)-OH		Azide
Fmoc-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Tyr(2-azidoethyl)-OH is unnatural Fmoc-protected Tyrosine derivative bears an azidoethyl substitution as reactive handle e.g. for biorthogonal conjugations, via a Cu(I)-catalyzed 1,3-dipolar Click cycloaddition with alkynes. And azido-UAAs can be employed as IR reporters . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-W011210

Fmoc-Pra-OH		Alkynes
Fmoc-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W008395

Fmoc-D-Pra-OH		Alkynes
Fmoc-D-Pra-OH is a Glycine (HY-Y0966) derivative . Fmoc-D-Pra-OH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W014258

(R)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid		Alkynes
(R)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid is a Glycine (HY-Y0966) derivative . (R)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-W014259

(S)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid		Alkynes
(S)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid is a Glycine (HY-Y0966) derivative . (S)-2-((tert-Butoxycarbonyl)amino)pent-4-ynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Cat. No.	Product Name		Classification

HY-W006103

I-bu-rG Phosphoramidite		Nucleoside Phosphoramidites
I-bu-rG Phosphoramidite is a phosphinamide monomer which can be used in the synthesis of nucleotides and nucleic acids.

HY-148170

L-I-OddU		Nucleosides and their Analogs
L-I-OddU, a L-5'-halo- dioxolane nucleoside analogue, is a potent and selective anti-Epstein-Barr virus (EBV) agent with an EC₅₀ value of 0.03μM. L-I-OddU has low cytotoxicity with a CC₅₀ value of 1000 nM. L-I-OddU has antiviral activity by suppressing replicative EBV DNA and viral protein synthesis .

HY-R00852

hsa-miR-378i mimic		MicroRNAs miRNA mimics
hsa-miR-378i mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R01687

hsa-miR-548i mimic		MicroRNAs miRNA mimics
hsa-miR-548i mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03056

mmu-miR-344i mimic		MicroRNAs miRNA mimics
mmu-miR-344i mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03472

mmu-miR-669i mimic		MicroRNAs miRNA mimics
mmu-miR-669i mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R04367

rno-miR-344i mimic		MicroRNAs miRNA mimics
rno-miR-344i mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RI00852

hsa-miR-378i inhibitor		MicroRNAs miRNA inhibitors
hsa-miR-378i inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI01687

hsa-miR-548i inhibitor		MicroRNAs miRNA inhibitors
hsa-miR-548i inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03056

mmu-miR-344i inhibitor		MicroRNAs miRNA inhibitors
mmu-miR-344i inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03472

mmu-miR-669i inhibitor		MicroRNAs miRNA inhibitors
mmu-miR-669i inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI04367

rno-miR-344i inhibitor		MicroRNAs miRNA inhibitors
rno-miR-344i inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-R00013

hsa-let-7i-3p mimic		MicroRNAs miRNA mimics
hsa-let-7i-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R00014

hsa-let-7i-5p mimic		MicroRNAs miRNA mimics
hsa-let-7i-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03181

mmu-miR-466i-3p mimic		MicroRNAs miRNA mimics
mmu-miR-466i-3p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-R03182

mmu-miR-466i-5p mimic		MicroRNAs miRNA mimics
mmu-miR-466i-5p mimics are small, chemically synthesized double-stranded RNAs that mimic endogenous miRNAs and enable miRNA functional analysis by up-regulation of miRNA activity.

HY-RS04265

EIF3I Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
EIF3I Human Pre-designed siRNA Set A contains three designed siRNAs for EIF3I gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS05903

GTF2I Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
GTF2I Human Pre-designed siRNA Set A contains three designed siRNAs for GTF2I gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS15349

UBE2I Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
UBE2I Human Pre-designed siRNA Set A contains three designed siRNAs for UBE2I gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS01799

CACNA1I Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
CACNA1I Human Pre-designed siRNA Set A contains three designed siRNAs for CACNA1I gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS10850

POLR2I Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
POLR2I Human Pre-designed siRNA Set A contains three designed siRNAs for POLR2I gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-R00852A

hsa-miR-378i agomir		MicroRNAs miRNA agomirs
hsa-miR-378i agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R01687A

hsa-miR-548i agomir		MicroRNAs miRNA agomirs
hsa-miR-548i agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03056A

mmu-miR-344i agomir		MicroRNAs miRNA agomirs
mmu-miR-344i agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03472A

mmu-miR-669i agomir		MicroRNAs miRNA agomirs
mmu-miR-669i agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R04367A

rno-miR-344i agomir		MicroRNAs miRNA agomirs
rno-miR-344i agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RS04083

DYNC1I1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
DYNC1I1 Human Pre-designed siRNA Set A contains three designed siRNAs for DYNC1I1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS04084

DYNC1I2 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
DYNC1I2 Human Pre-designed siRNA Set A contains three designed siRNAs for DYNC1I2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS06768

IL4I1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
IL4I1 Human Pre-designed siRNA Set A contains three designed siRNAs for IL4I1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS03064

COX4I1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
COX4I1 Human Pre-designed siRNA Set A contains three designed siRNAs for COX4I1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS03065

COX4I2 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
COX4I2 Human Pre-designed siRNA Set A contains three designed siRNAs for COX4I2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS14438

TGFB1I1 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
TGFB1I1 Human Pre-designed siRNA Set A contains three designed siRNAs for TGFB1I1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS14917

TP53I11 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
TP53I11 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53I11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS14918

TP53I13 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
TP53I13 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53I13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS14919

TP53I3 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
TP53I3 Human Pre-designed siRNA Set A contains three designed siRNAs for TP53I3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS09534

NR1I2 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
NR1I2 Human Pre-designed siRNA Set A contains three designed siRNAs for NR1I2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS09535

NR1I3 Human Pre-designed siRNA Set A		siRNAs Pre-designed siRNA Sets
NR1I3 Human Pre-designed siRNA Set A contains three designed siRNAs for NR1I3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RI00014

hsa-let-7i-5p inhibitor		MicroRNAs miRNA inhibitors
hsa-let-7i-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03181

mmu-miR-466i-3p inhibitor		MicroRNAs miRNA inhibitors
mmu-miR-466i-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI03182

mmu-miR-466i-5p inhibitor		MicroRNAs miRNA inhibitors
mmu-miR-466i-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI00013

hsa-let-7i-3p inhibitor		MicroRNAs miRNA inhibitors
hsa-let-7i-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.

HY-RI00852A

hsa-miR-378i antagomir		MicroRNAs miRNA antagomirs
hsa-miR-378i antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI01687A

hsa-miR-548i antagomir		MicroRNAs miRNA antagomirs
hsa-miR-548i antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI04367A

rno-miR-344i antagomir		MicroRNAs miRNA antagomirs
rno-miR-344i antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03056A

mmu-miR-344i antagomir		MicroRNAs miRNA antagomirs
mmu-miR-344i antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-RI03472A

mmu-miR-669i antagomir		MicroRNAs miRNA antagomirs
mmu-miR-669i antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00013A

hsa-let-7i-3p agomir		MicroRNAs miRNA agomirs
hsa-let-7i-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R00014A

hsa-let-7i-5p agomir		MicroRNAs miRNA agomirs
hsa-let-7i-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03181A

mmu-miR-466i-3p agomir		MicroRNAs miRNA agomirs
mmu-miR-466i-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

HY-R03182A

mmu-miR-466i-5p agomir		MicroRNAs miRNA agomirs
mmu-miR-466i-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.

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